TMEM16F activation by Ca<sup>2+</sup> triggers plasma membrane expansion and directs PD-1 trafficking.

Bricogne, Christopher; Fine, Michael; Pereira, Pedro M; Sung, Julia; Tijani, Maha; Wang, Youxue; Henriques, Ricardo; Collins, Mary K; Hilgemann, Donald W

TMEM16F activation by Ca²⁺ triggers plasma membrane expansion and directs PD-1 trafficking.

Bricogne, Christopher; Fine, Michael; Pereira, Pedro M; Sung, Julia; Tijani, Maha; Wang, Youxue; Henriques, Ricardo; Collins, Mary K; Hilgemann, Donald W.

Afiliação

Bricogne C; UCL Cancer Institute, University College London, Gower St, London, UK.
Fine M; University of Texas Southwestern Medical Center, Department of Physiology, Dallas, Texas, USA.
Pereira PM; MRC Laboratory for Molecular Cell Biology, University College London, Gower St, London, UK.
Sung J; National Institute for Biological Standards and Control, Blanche Lane, South Mimms, Herts, UK.
Tijani M; National Institute for Biological Standards and Control, Blanche Lane, South Mimms, Herts, UK.
Wang Y; University of Texas Southwestern Medical Center, Department of Physiology, Dallas, Texas, USA.
Henriques R; MRC Laboratory for Molecular Cell Biology, University College London, Gower St, London, UK.
Collins MK; UCL Cancer Institute, University College London, Gower St, London, UK. mary.collins@oist.jp.
Hilgemann DW; National Institute for Biological Standards and Control, Blanche Lane, South Mimms, Herts, UK. mary.collins@oist.jp.

Sci Rep ; 9(1): 619, 2019 01 24.

Article em En | MEDLINE | ID: mdl-30679690

Assuntos

Anoctaminas/metabolismo; Cálcio/metabolismo; Membrana Celular/metabolismo; Proteínas de Transferência de Fosfolipídeos/metabolismo; Receptor de Morte Celular Programada 1/metabolismo; Anoctaminas/genética; Sistemas CRISPR-Cas/genética; Linhagem Celular; Citometria de Fluxo; Humanos; Células Jurkat; Lentivirus/genética; Microscopia Confocal; Proteínas de Transferência de Fosfolipídeos/genética; Receptor de Morte Celular Programada 1/genética

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Membrana Celular / Cálcio / Proteínas de Transferência de Fosfolipídeos / Receptor de Morte Celular Programada 1 / Anoctaminas Limite: Humans Idioma: En Revista: Sci Rep Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Reino Unido

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