Antecedent Administration of Glutamine Benefits the Homeostasis of CD4<sup>+</sup> T Cells and Attenuates Lung Injury in Mice With Gut-Derived Polymicrobial Sepsis.

Lei, Cing-Syuan; Wu, Jin-Ming; Lee, Po-Chu; Kuo, Ting-Chun; Chen, Po-Da; Hou, Yu-Chen; Yeh, Sung-Ling; Lin, Ming-Tsan

Antecedent Administration of Glutamine Benefits the Homeostasis of CD4⁺ T Cells and Attenuates Lung Injury in Mice With Gut-Derived Polymicrobial Sepsis.

Lei, Cing-Syuan; Wu, Jin-Ming; Lee, Po-Chu; Kuo, Ting-Chun; Chen, Po-Da; Hou, Yu-Chen; Yeh, Sung-Ling; Lin, Ming-Tsan.

Afiliação

Lei CS; Department of Surgery, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan.
Wu JM; Department of Surgery, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan.
Lee PC; Department of Surgery, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan.
Kuo TC; Department of Surgery, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan.
Chen PD; Department of Surgery, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan.
Hou YC; Master Program in Food Safety, College of Nutrition, Taipei Medical University, Taipei, Taiwan.
Yeh SL; School of Nutrition and Health Sciences, College of Nutrition, Taipei Medical University, Taipei, Taiwan.
Lin MT; Department of Surgery, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan.

JPEN J Parenter Enteral Nutr ; 43(7): 927-936, 2019 09.

Article em En | MEDLINE | ID: mdl-30714626

Assuntos

Linfócitos T CD4-Positivos/metabolismo; Microbioma Gastrointestinal; Glutamina/uso terapêutico; Inflamação/prevenção & controle; Lesão Pulmonar/prevenção & controle; Pulmão/efeitos dos fármacos; Sepse; Animais; Antígenos CD/metabolismo; Antígenos de Diferenciação de Linfócitos T/metabolismo; Linfócitos T CD8-Positivos/metabolismo; Dieta; Glutamina/administração & dosagem; Glutamina/farmacologia; Homeostase; Inflamação/etiologia; Inflamação/metabolismo; Interferon gama/metabolismo; Interleucina-17/metabolismo; Interleucina-4/metabolismo; Lectinas Tipo C/metabolismo; Pulmão/metabolismo; Lesão Pulmonar/etiologia; Masculino; Camundongos Endogâmicos C57BL; Distribuição Aleatória; Sepse/complicações; Sepse/metabolismo; Sepse/microbiologia; Baço; Subpopulações de Linfócitos T/metabolismo; Linfócitos T Reguladores/metabolismo

Palavras-chave

CD4 T cells; T helper cell; T regulatory cell; glutamine; sepsis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfócitos T CD4-Positivos / Sepse / Lesão Pulmonar / Microbioma Gastrointestinal / Glutamina / Inflamação / Pulmão Tipo de estudo: Etiology_studies Limite: Animals Idioma: En Revista: JPEN J Parenter Enteral Nutr Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Taiwan

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