Glucose-6-Phosphate dehydrogenase deficiency incidence in a Hispanic population.
J Neonatal Perinatal Med
; 12(2): 203-207, 2019.
Article
em En
| MEDLINE
| ID: mdl-30741698
ABSTRACT
Glucose-6-phosphate dehydrogenase deficiency (D-G6PD) is a common erythroenzymopathy that needs to be addressed as an important public health issue. Proper population monitoring is needed to anticipate clinical complications. A joint venture between Genomi-k (a Mexican company focused on newborn screening) and several university researchers conducted a retrospetive study for D-G6PD based on 156,152 newborn screening reports belonging to the Mexican population comprising a period of 10 years. We identified 540 male newborns affected with this deficiency, representing an incidence of 6.78 cases per 1,000 newborn males. A single double mutation of G202AA376G was detected in 97.22% of cases. In regions where there is an absence of a national centralized health data for D-G6PD, information from a non-probabilistic large population sample can be used as a national incidence subrogate.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Deficiência de Glucosefosfato Desidrogenase
Tipo de estudo:
Incidence_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Humans
/
Male
/
Newborn
País/Região como assunto:
Mexico
Idioma:
En
Revista:
J Neonatal Perinatal Med
Ano de publicação:
2019
Tipo de documento:
Article
País de afiliação:
México