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APOE4-mediated amyloid-ß pathology depends on its neuronal receptor LRP1.
Tachibana, Masaya; Holm, Marie-Louise; Liu, Chia-Chen; Shinohara, Mitsuru; Aikawa, Tomonori; Oue, Hiroshi; Yamazaki, Yu; Martens, Yuka A; Murray, Melissa E; Sullivan, Patrick M; Weyer, Kathrin; Glerup, Simon; Dickson, Dennis W; Bu, Guojun; Kanekiyo, Takahisa.
Afiliação
  • Tachibana M; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA.
  • Holm ML; United Graduate School of Child Development, Osaka University, Osaka, Japan.
  • Liu CC; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA.
  • Shinohara M; Department of Biomedicine, Aarhus University, Aarhus, Denmark.
  • Aikawa T; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA.
  • Oue H; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA.
  • Yamazaki Y; Department of Aging Neurobiology, National Center for Geriatrics and Gerontology, Aichi, Japan.
  • Martens YA; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA.
  • Murray ME; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA.
  • Sullivan PM; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA.
  • Weyer K; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA.
  • Glerup S; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA.
  • Dickson DW; Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA.
  • Bu G; Department of Biomedicine, Aarhus University, Aarhus, Denmark.
  • Kanekiyo T; Department of Biomedicine, Aarhus University, Aarhus, Denmark.
J Clin Invest ; 129(3): 1272-1277, 2019 03 01.
Article em En | MEDLINE | ID: mdl-30741718
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fragmentos de Peptídeos / Peptídeos beta-Amiloides / Proteína-1 Relacionada a Receptor de Lipoproteína de Baixa Densidade / Apolipoproteína E4 / Doença de Alzheimer / Hipocampo Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Clin Invest Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fragmentos de Peptídeos / Peptídeos beta-Amiloides / Proteína-1 Relacionada a Receptor de Lipoproteína de Baixa Densidade / Apolipoproteína E4 / Doença de Alzheimer / Hipocampo Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Clin Invest Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos