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Niraparib activates interferon signaling and potentiates anti-PD-1 antibody efficacy in tumor models.
Wang, Zebin; Sun, Kaiming; Xiao, Yonghong; Feng, Bin; Mikule, Keith; Ma, XiaoYan; Feng, Ningping; Vellano, Christopher P; Federico, Lorenzo; Marszalek, Joseph R; Mills, Gordon B; Hanke, Jeffrey; Ramaswamy, Sridhar; Wang, Jing.
Afiliação
  • Wang Z; TESARO, Inc, Waltham, MA, 02451, USA.
  • Sun K; TESARO, Inc, Waltham, MA, 02451, USA.
  • Xiao Y; TESARO, Inc, Waltham, MA, 02451, USA.
  • Feng B; TESARO, Inc, Waltham, MA, 02451, USA.
  • Mikule K; TESARO, Inc, Waltham, MA, 02451, USA.
  • Ma X; Center for Co-Clinical Trials, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Feng N; Center for Co-Clinical Trials, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Vellano CP; Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Federico L; Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Marszalek JR; Center for Co-Clinical Trials, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Mills GB; Institute for Applied Cancer Science, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Hanke J; Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Ramaswamy S; TESARO, Inc, Waltham, MA, 02451, USA.
  • Wang J; TESARO, Inc, Waltham, MA, 02451, USA.
Sci Rep ; 9(1): 1853, 2019 02 12.
Article em En | MEDLINE | ID: mdl-30755715
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Piperidinas / Neoplasias da Mama / Interferons / Receptor de Morte Celular Programada 1 / Inibidores de Poli(ADP-Ribose) Polimerases / Indazóis Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Sci Rep Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Piperidinas / Neoplasias da Mama / Interferons / Receptor de Morte Celular Programada 1 / Inibidores de Poli(ADP-Ribose) Polimerases / Indazóis Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Sci Rep Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos