Pharmacological Reactivation of the Silenced <i>FMR1</i> Gene as a Targeted Therapeutic Approach for Fragile X Syndrome.

Kumari, Daman; Gazy, Inbal; Usdin, Karen

Pharmacological Reactivation of the Silenced FMR1 Gene as a Targeted Therapeutic Approach for Fragile X Syndrome.

Kumari, Daman; Gazy, Inbal; Usdin, Karen.

Afiliação

Kumari D; Section on Gene Structure and Disease, Laboratory of Cell and Molecular Biology, National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA. damank@niddk.nih.gov.
Gazy I; Section on Gene Structure and Disease, Laboratory of Cell and Molecular Biology, National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA. inbal.gazy@nih.gov.
Usdin K; Section on Gene Structure and Disease, Laboratory of Cell and Molecular Biology, National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA. ku@helix.nih.gov.

Brain Sci ; 9(2)2019 Feb 12.

Article em En | MEDLINE | ID: mdl-30759772

Palavras-chave

DNA methylation; FMR1; FMRP; PRC2; RNA:DNA hybrid; fragile X syndrome; gene reactivation; histone methylation

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: Brain Sci Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: Brain Sci Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos