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Squalene accumulation in cholesterol auxotrophic lymphomas prevents oxidative cell death.
Garcia-Bermudez, Javier; Baudrier, Lou; Bayraktar, Erol Can; Shen, Yihui; La, Konnor; Guarecuco, Rohiverth; Yucel, Burcu; Fiore, Danilo; Tavora, Bernardo; Freinkman, Elizaveta; Chan, Sze Ham; Lewis, Caroline; Min, Wei; Inghirami, Giorgio; Sabatini, David M; Birsoy, Kivanç.
Afiliação
  • Garcia-Bermudez J; Laboratory of Metabolic Regulation and Genetics, The Rockefeller University, New York, NY, USA.
  • Baudrier L; Laboratory of Metabolic Regulation and Genetics, The Rockefeller University, New York, NY, USA.
  • Bayraktar EC; Laboratory of Metabolic Regulation and Genetics, The Rockefeller University, New York, NY, USA.
  • Shen Y; Department of Chemistry, Columbia University, New York, NY, USA.
  • La K; Kavli Institute for Brain Science, Columbia University, New York, NY, USA.
  • Guarecuco R; Laboratory of Metabolic Regulation and Genetics, The Rockefeller University, New York, NY, USA.
  • Yucel B; Laboratory of Metabolic Regulation and Genetics, The Rockefeller University, New York, NY, USA.
  • Fiore D; Laboratory of Metabolic Regulation and Genetics, The Rockefeller University, New York, NY, USA.
  • Tavora B; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY, USA.
  • Freinkman E; Department of Molecular Biotechnology and Health Sciences, University of Turin, Turin, Italy.
  • Chan SH; Laboratory of Metabolic Regulation and Genetics, The Rockefeller University, New York, NY, USA.
  • Lewis C; Whitehead Institute for Biomedical Research, Cambridge, MA, USA.
  • Min W; Whitehead Institute for Biomedical Research, Cambridge, MA, USA.
  • Inghirami G; Whitehead Institute for Biomedical Research, Cambridge, MA, USA.
  • Sabatini DM; Department of Chemistry, Columbia University, New York, NY, USA.
  • Birsoy K; Kavli Institute for Brain Science, Columbia University, New York, NY, USA.
Nature ; 567(7746): 118-122, 2019 03.
Article em En | MEDLINE | ID: mdl-30760928
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Esqualeno / Colesterol / Apoptose / Linfoma Anaplásico de Células Grandes / Estresse Oxidativo Limite: Adult / Aged / Animals / Female / Humans / Male Idioma: En Revista: Nature Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Esqualeno / Colesterol / Apoptose / Linfoma Anaplásico de Células Grandes / Estresse Oxidativo Limite: Adult / Aged / Animals / Female / Humans / Male Idioma: En Revista: Nature Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos