epic2 efficiently finds diffuse domains in ChIP-seq data.
Bioinformatics
; 35(21): 4392-4393, 2019 11 01.
Article
em En
| MEDLINE
| ID: mdl-30923821
ABSTRACT
SUMMARY:
Data from chromatin immunoprecipitation (ChIP) followed by high-throughput sequencing (ChIP-seq) generally contain either narrow peaks or broad and diffusely enriched domains. The SICER ChIP-seq caller has proven adept at finding diffuse domains in ChIP-seq data, but it is slow, requires much memory, needs manual installation steps and is hard to use. epic2 is a complete rewrite of SICER that is focused on speed, low memory overhead and ease-of-use. AVAILABILITY AND IMPLEMENTATION The MIT-licensed code is available at https//github.com/biocore-ntnu/epic2. SUPPLEMENTARY INFORMATION Supplementary data are available at Bioinformatics online.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Sequenciamento de Nucleotídeos em Larga Escala
/
Sequenciamento de Cromatina por Imunoprecipitação
Idioma:
En
Revista:
Bioinformatics
Assunto da revista:
INFORMATICA MEDICA
Ano de publicação:
2019
Tipo de documento:
Article
País de afiliação:
Noruega