Screening of antibacterial drugs for antimicrobial activity against Pythium insidiosum.
Med Mycol
; 57(4): 523-525, 2019 Jun 01.
Article
em En
| MEDLINE
| ID: mdl-30929019
ABSTRACT
We tested 25 isolates of Pythium insidiosum to investigate their susceptibility to antibacterial drugs that act through inhibition of protein synthesis or other mechanisms of action. We observed that tetracycline, erythromycin, linezolid, nitrofurantoin, Synercid (quinupristin and dalfopristin), chloramphenicol, clindamycin, cetrimide, and crystal violet had inhibitory activity against P. insidiosum. Those in vitro results suggest that antibacterials that inhibit protein synthesis should be the primary antimicrobials investigated for the treatment of pythiosis in animals and humans.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Pythium
/
Antibacterianos
/
Antifúngicos
Tipo de estudo:
Diagnostic_studies
/
Screening_studies
Limite:
Humans
Idioma:
En
Revista:
Med Mycol
Assunto da revista:
MEDICINA VETERINARIA
/
MICROBIOLOGIA
Ano de publicação:
2019
Tipo de documento:
Article
País de afiliação:
Brasil