Impact of the clinical frailty scale on mid-term mortality in patients with ST-elevated myocardial infarction.
Int J Cardiol Heart Vasc
; 22: 192-198, 2019 Mar.
Article
em En
| MEDLINE
| ID: mdl-30963094
ABSTRACT
BACKGROUND:
"Frailty" is associated with poor prognosis in ST-elevated myocardial infarction (STEMI). However, there is little data regarding the impact of the Canadian Study of Health and Aging Clinical Frailty Scale (CFS), a simple and semiquantitative tool for assessing frailty, on mid-term mortality in STEMI patients.METHODS:
A total of 354 consecutive STEMI patients (mean age 69.8⯱â¯12.4â¯years; male 76.6%) who underwent percutaneous intervention between July 2014 and March 2017 were retrospectively reviewed. The study endpoint was mid-term mortality according to the CFS classification. Furthermore, in order to clarify the impact of CFS upon admission on mid-term mortality, the independent predictors of all-cause death were evaluated.RESULTS:
Patients were categorized into three groups (CFS 1-3, nâ¯=â¯281; CFS 4-5, nâ¯=â¯62; and CFS 6-7, nâ¯=â¯11). During the study period (median 474â¯days), all-cause death was observed in 39 patients. After multivariate Cox regression analysis, higher CFS (adjusted hazard ratio [HR] 2.34, 95% confidence interval [CI] 1.43-3.85, pâ¯<â¯0.001), higher Killip score (adjusted HR 2.46, 95%CI 1.30-5.78, pâ¯=â¯0.002), and lower serum albumin level (adjusted HR 4.29, 95%CI 2.16-8.51, pâ¯<â¯0.001) were significantly associated with an increased risk of all-cause death.CONCLUSION:
In conclusion, severe frailty was associated with mid-term mortality in STEMI patients who underwent PCI.
Texto completo:
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Base de dados:
MEDLINE
Tipo de estudo:
Prognostic_studies
Idioma:
En
Revista:
Int J Cardiol Heart Vasc
Ano de publicação:
2019
Tipo de documento:
Article
País de afiliação:
Japão