MicroRNA-365 Knockdown Prevents Ischemic Neuronal Injury by Activating Oxidation Resistance 1-Mediated Antioxidant Signals.

Mo, Jia-Lin; Pan, Zhi-Guang; Chen, Xiao; Lei, Yu; Lv, Ling-Ling; Qian, Cheng; Sun, Feng-Yan

Mo, Jia-Lin; Pan, Zhi-Guang; Chen, Xiao; Lei, Yu; Lv, Ling-Ling; Qian, Cheng; Sun, Feng-Yan.

Afiliação

Mo JL; Department of Neurobiology and Institute for Basic Research on Aging and Medicine, School of Basic Medical Sciences, Fudan University, Shanghai, 200032, China.
Pan ZG; State Key Laboratory of Medical Neurobiology, School of Basic Medical Sciences, Fudan University, Shanghai, 200032, China.
Chen X; Department of Neurosurgery, National Clinical Research Center for Aging and Medicine, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, 200032, China.
Lei Y; State Key Laboratory of Medical Neurobiology, School of Basic Medical Sciences, Fudan University, Shanghai, 200032, China.
Lv LL; Department of Neurobiology and Institute for Basic Research on Aging and Medicine, School of Basic Medical Sciences, Fudan University, Shanghai, 200032, China.
Qian C; State Key Laboratory of Medical Neurobiology, School of Basic Medical Sciences, Fudan University, Shanghai, 200032, China.
Sun FY; Department of Neurobiology and Institute for Basic Research on Aging and Medicine, School of Basic Medical Sciences, Fudan University, Shanghai, 200032, China.

Neurosci Bull ; 35(5): 815-825, 2019 Oct.

Article em En | MEDLINE | ID: mdl-30977043

Assuntos

Antioxidantes/metabolismo; Isquemia Encefálica/metabolismo; MicroRNAs/metabolismo; Proteínas Mitocondriais/metabolismo; Neuroproteção/fisiologia; Estresse Oxidativo/fisiologia; Animais; Isquemia Encefálica/prevenção & controle; Células Cultivadas; Técnicas de Silenciamento de Genes/métodos; Peróxido de Hidrogênio/toxicidade; Masculino; MicroRNAs/antagonistas & inibidores; Ratos; Ratos Sprague-Dawley

Palavras-chave

Ischemic stroke; MicroRNA; Neuronal damage; Neuroprotection; Oxidative stress

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Isquemia Encefálica / Estresse Oxidativo / Proteínas Mitocondriais / MicroRNAs / Neuroproteção / Antioxidantes Limite: Animals Idioma: En Revista: Neurosci Bull Assunto da revista: NEUROLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China

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