Distinct cellular responses to replication stress leading to apoptosis or senescence.

Lukásová, Emilie; Rezácová, Martina; Bacíková, Alena; Sebejová, Ludmila; Vávrová, Jirina; Kozubek, Stanislav

Lukásová, Emilie; Rezácová, Martina; Bacíková, Alena; Sebejová, Ludmila; Vávrová, Jirina; Kozubek, Stanislav.

Afiliação

Lukásová E; Department of Cell Biology and Radiobiology, Institute of Biophysics, The Czech Academy of Sciences, Brno, Czech Republic.
Rezácová M; Department of Medical Biochemistry, Faculty of Medicine in Hradec Králové, Charles University in Prague, Hradec Králové, Czech Republic.
Bacíková A; Department of Cell Biology and Radiobiology, Institute of Biophysics, The Czech Academy of Sciences, Brno, Czech Republic.
Sebejová L; Department of Internal Medicine - Hematology and Oncology, University Hospital Brno and Faculty of Medicine, Masaryk University, Brno, Czech Republic.
Vávrová J; Department of Radiobiology, Faculty of Military Health Sciences Hradec Králové, University of Defence Brno, Hradec Králové, Czech Republic.
Kozubek S; Department of Cell Biology and Radiobiology, Institute of Biophysics, The Czech Academy of Sciences, Brno, Czech Republic.

FEBS Open Bio ; 9(5): 870-890, 2019 05.

Article em En | MEDLINE | ID: mdl-30982228

Assuntos

Apoptose/fisiologia; Senescência Celular/fisiologia; Replicação do DNA/fisiologia; Linhagem Celular Tumoral; Humanos; Lamina Tipo A/metabolismo; Células MCF-7; Mutação; Proteína Supressora de Tumor p53/genética; Vidarabina/análogos & derivados; Vidarabina/farmacologia

Palavras-chave

ATR inhibitor; Chk1 inhibitor; apoptosis; lamin B receptor; replication stress; senescence

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Senescência Celular / Apoptose / Replicação do DNA Limite: Humans Idioma: En Revista: FEBS Open Bio Ano de publicação: 2019 Tipo de documento: Article País de afiliação: República Tcheca

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google