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A Subset of New Platinum Antitumor Agents Kills Cells by a Multimodal Mechanism of Action Also Involving Changes in the Organization of the Microtubule Cytoskeleton.
Kostrhunova, Hana; Zajac, Juraj; Novohradsky, Vojtech; Kasparkova, Jana; Malina, Jaroslav; Aldrich-Wright, Janice R; Petruzzella, Emanuele; Sirota, Roman; Gibson, Dan; Brabec, Viktor.
Afiliação
  • Kostrhunova H; Czech Academy of Sciences , Institute of Biophysics , Kralovopolska 135 , CZ-61265 Brno , Czech Republic.
  • Zajac J; Czech Academy of Sciences , Institute of Biophysics , Kralovopolska 135 , CZ-61265 Brno , Czech Republic.
  • Novohradsky V; Czech Academy of Sciences , Institute of Biophysics , Kralovopolska 135 , CZ-61265 Brno , Czech Republic.
  • Kasparkova J; Czech Academy of Sciences , Institute of Biophysics , Kralovopolska 135 , CZ-61265 Brno , Czech Republic.
  • Malina J; Czech Academy of Sciences , Institute of Biophysics , Kralovopolska 135 , CZ-61265 Brno , Czech Republic.
  • Aldrich-Wright JR; School of Science and Health , Western Sydney University , Penrith South DC 1797 , NSW , Australia.
  • Petruzzella E; Institute for Drug Research, School of Pharmacy , The Hebrew University , Jerusalem 91120 , Israel.
  • Sirota R; Institute for Drug Research, School of Pharmacy , The Hebrew University , Jerusalem 91120 , Israel.
  • Gibson D; Institute for Drug Research, School of Pharmacy , The Hebrew University , Jerusalem 91120 , Israel.
  • Brabec V; Czech Academy of Sciences , Institute of Biophysics , Kralovopolska 135 , CZ-61265 Brno , Czech Republic.
J Med Chem ; 62(10): 5176-5190, 2019 05 23.
Article em En | MEDLINE | ID: mdl-31030506
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Compostos Organoplatínicos / Citoesqueleto / Microtúbulos / Antineoplásicos Limite: Animals / Female / Humans Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: República Tcheca
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Compostos Organoplatínicos / Citoesqueleto / Microtúbulos / Antineoplásicos Limite: Animals / Female / Humans Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: República Tcheca