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Impact of Phosphodiesterase 4 Inhibition on the Operational Efficacy, Response Maxima, and Kinetics of Indacaterol-Induced Gene Expression Changes in BEAS-2B Airway Epithelial Cells: A Global Transcriptomic Analysis.
Joshi, Radhika; Yan, Dong; Hamed, Omar; Mostafa, Mahmoud M; Joshi, Taruna; Newton, Robert; Giembycz, Mark A.
Afiliação
  • Joshi R; Departments of Physiology and Pharmacology (R.J., D.Y., O.H., T.J., M.A.G.) and Cell Biology and Anatomy (M.M.M., R.N.), Airways Inflammation Research Group, Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
  • Yan D; Departments of Physiology and Pharmacology (R.J., D.Y., O.H., T.J., M.A.G.) and Cell Biology and Anatomy (M.M.M., R.N.), Airways Inflammation Research Group, Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
  • Hamed O; Departments of Physiology and Pharmacology (R.J., D.Y., O.H., T.J., M.A.G.) and Cell Biology and Anatomy (M.M.M., R.N.), Airways Inflammation Research Group, Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
  • Mostafa MM; Departments of Physiology and Pharmacology (R.J., D.Y., O.H., T.J., M.A.G.) and Cell Biology and Anatomy (M.M.M., R.N.), Airways Inflammation Research Group, Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
  • Joshi T; Departments of Physiology and Pharmacology (R.J., D.Y., O.H., T.J., M.A.G.) and Cell Biology and Anatomy (M.M.M., R.N.), Airways Inflammation Research Group, Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
  • Newton R; Departments of Physiology and Pharmacology (R.J., D.Y., O.H., T.J., M.A.G.) and Cell Biology and Anatomy (M.M.M., R.N.), Airways Inflammation Research Group, Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
  • Giembycz MA; Departments of Physiology and Pharmacology (R.J., D.Y., O.H., T.J., M.A.G.) and Cell Biology and Anatomy (M.M.M., R.N.), Airways Inflammation Research Group, Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada giembycz@ucalgary.ca.
Mol Pharmacol ; 96(1): 56-72, 2019 07.
Article em En | MEDLINE | ID: mdl-31036559
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Quinolonas / Perfilação da Expressão Gênica / Inibidores da Fosfodiesterase 4 / Indanos / Pulmão Tipo de estudo: Guideline Limite: Humans Idioma: En Revista: Mol Pharmacol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Canadá
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Quinolonas / Perfilação da Expressão Gênica / Inibidores da Fosfodiesterase 4 / Indanos / Pulmão Tipo de estudo: Guideline Limite: Humans Idioma: En Revista: Mol Pharmacol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Canadá