Dynamic changes of metabolomics and expression of candicidin biosynthesis gene cluster caused by the presence of a pleiotropic regulator AdpA in Streptomyces ZYJ-6.

Liu, Xiaoyun; Sun, Xiaojuan; He, Weimin; Tian, Xiwei; Zhuang, Yingping; Chu, Ju

Liu, Xiaoyun; Sun, Xiaojuan; He, Weimin; Tian, Xiwei; Zhuang, Yingping; Chu, Ju.

Afiliação

Liu X; State Key Laboratory of Bioreactor Engineering, School of Biochemical Engineering, East China University of Science and Technology, Room 413, Building 18, Shanghai, 200237, People's Republic of China.
Sun X; State Key Laboratory of Bioreactor Engineering, School of Biochemical Engineering, East China University of Science and Technology, Room 413, Building 18, Shanghai, 200237, People's Republic of China.
He W; State Key Laboratory of Bioreactor Engineering, School of Biochemical Engineering, East China University of Science and Technology, Room 413, Building 18, Shanghai, 200237, People's Republic of China.
Tian X; State Key Laboratory of Bioreactor Engineering, School of Biochemical Engineering, East China University of Science and Technology, Room 413, Building 18, Shanghai, 200237, People's Republic of China.
Zhuang Y; State Key Laboratory of Bioreactor Engineering, School of Biochemical Engineering, East China University of Science and Technology, Room 413, Building 18, Shanghai, 200237, People's Republic of China.
Chu J; State Key Laboratory of Bioreactor Engineering, School of Biochemical Engineering, East China University of Science and Technology, Room 413, Building 18, Shanghai, 200237, People's Republic of China. juchu@ecust.edu.cn.

Bioprocess Biosyst Eng ; 42(8): 1353-1365, 2019 Aug.

Article em En | MEDLINE | ID: mdl-31062087

Assuntos

Proteínas de Bactérias/metabolismo; Candicidina/biossíntese; Regulação Bacteriana da Expressão Gênica; Família Multigênica; Streptomyces/metabolismo; Transativadores/metabolismo; Proteínas de Bactérias/genética; Metabolômica; Streptomyces/genética; Transativadores/genética

Palavras-chave

Candicidin; FBA; Metabolomics; Streptomyces; qRT-PCR

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Streptomyces / Proteínas de Bactérias / Candicidina / Regulação Bacteriana da Expressão Gênica / Transativadores / Família Multigênica Idioma: En Revista: Bioprocess Biosyst Eng Assunto da revista: BIOTECNOLOGIA / ENGENHARIA BIOMEDICA Ano de publicação: 2019 Tipo de documento: Article

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