Impact of Herpes Simplex Virus Type 2 and Human Immunodeficiency Virus Dual Infection on Female Genital Tract Mucosal Immunity and the Vaginal Microbiome.

Keller, Marla J; Huber, Ashley; Espinoza, Lilia; Serrano, Myrna G; Parikh, Hardik I; Buck, Gregory A; Gold, Jeremy A; Wu, Yiqun; Wang, Tao; Herold, Betsy C

Keller, Marla J; Huber, Ashley; Espinoza, Lilia; Serrano, Myrna G; Parikh, Hardik I; Buck, Gregory A; Gold, Jeremy A; Wu, Yiqun; Wang, Tao; Herold, Betsy C.

Afiliação

Keller MJ; Departments of Medicine, Albert Einstein College of Medicine, Bronx, New York.
Huber A; Departments of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York.
Espinoza L; Present Affiliation: Department of Obstetrics, Gynecology and Reproductive Medicine, Stony Brook University School of Medicine, Stony Brook, New York.
Serrano MG; Departments of Medicine, Albert Einstein College of Medicine, Bronx, New York.
Parikh HI; Department of Microbiology and Immunology, Virginia Commonwealth University, Richmond.
Buck GA; Center for Microbiome Engineering and Data Analysis, Virginia Commonwealth University, Richmond.
Gold JA; School of Medicine Research Computing, University of Virginia, Charlottesville.
Wu Y; Department of Microbiology and Immunology, Virginia Commonwealth University, Richmond.
Wang T; Center for Microbiome Engineering and Data Analysis, Virginia Commonwealth University, Richmond.
Herold BC; Computer Science Department, Virginia Commonwealth University, Richmond.

J Infect Dis ; 220(5): 852-861, 2019 07 31.

Article em En | MEDLINE | ID: mdl-31111902

Assuntos

Genitália Feminina/microbiologia; Infecções por HIV/complicações; Herpes Genital/imunologia; Herpesvirus Humano 2/imunologia; Imunidade nas Mucosas/imunologia; Microbiota/fisiologia; Vagina/microbiologia; Adulto; Anti-Infecciosos/farmacologia; Coinfecção/virologia; Disbiose; Feminino; Herpes Genital/epidemiologia; Herpes Genital/virologia; Humanos; Interferon gama; Lactobacillus; Pessoa de Meia-Idade; Muramidase; Inibidor Secretado de Peptidases Leucocitárias; Fator de Necrose Tumoral alfa; Vagina/virologia; Eliminação de Partículas Virais; beta-Defensinas

Palavras-chave

herpes simplex virus; human immunodeficiency virus; microbiome; mucosal immunity; vaginal dysbiosis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vagina / Herpes Genital / Infecções por HIV / Herpesvirus Humano 2 / Imunidade nas Mucosas / Microbiota / Genitália Feminina Limite: Adult / Female / Humans / Middle aged Idioma: En Revista: J Infect Dis Ano de publicação: 2019 Tipo de documento: Article

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