p90 ribosomal S6 kinase (RSK) phosphorylates myosin phosphatase and thereby controls edge dynamics during cell migration.

Samson, Shiela C; Elliott, Andrew; Mueller, Brian D; Kim, Yung; Carney, Keith R; Bergman, Jared P; Blenis, John; Mendoza, Michelle C

Samson, Shiela C; Elliott, Andrew; Mueller, Brian D; Kim, Yung; Carney, Keith R; Bergman, Jared P; Blenis, John; Mendoza, Michelle C.

Afiliação

Samson SC; Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah 84112 and.
Elliott A; Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah 84112 and.
Mueller BD; Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah 84112 and.
Kim Y; Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah 84112 and.
Carney KR; Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah 84112 and.
Bergman JP; Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah 84112 and.
Blenis J; Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115.
Mendoza MC; Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah 84112 and; Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115. Electronic address: Michelle.Mendoza@hci.utah.edu.

J Biol Chem ; 294(28): 10846-10862, 2019 07 12.

Article em En | MEDLINE | ID: mdl-31138649

Assuntos

Movimento Celular/fisiologia; Sistema de Sinalização das MAP Quinases/fisiologia; Proteínas Quinases S6 Ribossômicas 90-kDa/metabolismo; Citoesqueleto de Actina/metabolismo; Actomiosina/metabolismo; Animais; Células COS; Linhagem Celular; Chlorocebus aethiops; Citoesqueleto/metabolismo; Citoesqueleto/fisiologia; Humanos; Contração Muscular; Fosfatase de Miosina-de-Cadeia-Leve/metabolismo; Fosfatase de Miosina-de-Cadeia-Leve/fisiologia; Miosinas/metabolismo; Fosforilação; Ligação Proteica; Proteínas Quinases S6 Ribossômicas 90-kDa/fisiologia; Transdução de Sinais; Quinases Associadas a rho/metabolismo

Palavras-chave

Rho kinase (ROCK); cell migration; cell motility; cell signaling; cytoskeleton; extracellular-signal-regulated kinase (ERK); myosin; myosin phosphatase targeting subunit (MYPT1); p90 ribosomal S6 kinase (RSK)

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Movimento Celular / Sistema de Sinalização das MAP Quinases / Proteínas Quinases S6 Ribossômicas 90-kDa Limite: Animals / Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2019 Tipo de documento: Article

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