Is Optogenetic Activation of Vglut1-Positive Aß Low-Threshold Mechanoreceptors Sufficient to Induce Tactile Allodynia in Mice after Nerve Injury?

Chamessian, Alexander; Matsuda, Megumi; Young, Michael; Wang, Michelle; Zhang, Zhi-Jun; Liu, Di; Tobin, Brielle; Xu, Zhen-Zhong; Van de Ven, Thomas; Ji, Ru-Rong

Chamessian, Alexander; Matsuda, Megumi; Young, Michael; Wang, Michelle; Zhang, Zhi-Jun; Liu, Di; Tobin, Brielle; Xu, Zhen-Zhong; Van de Ven, Thomas; Ji, Ru-Rong.

Afiliação

Chamessian A; Department of Anesthesiology, alexander.chamessian@duke.edu.
Matsuda M; Department of Neurobiology, and.
Young M; Medical Scientist Training Program, Duke University School of Medicine, Durham, North Carolina 27710.
Wang M; Department of Anesthesiology.
Zhang ZJ; Department of Neurobiology, and.
Liu D; Department of Anesthesiology.
Tobin B; Department of Anesthesiology.
Xu ZZ; Department of Anesthesiology.
Van de Ven T; Department of Anesthesiology.
Ji RR; Department of Anesthesiology.

J Neurosci ; 39(31): 6202-6215, 2019 07 31.

Article em En | MEDLINE | ID: mdl-31152125

Assuntos

Hiperalgesia/fisiopatologia; Mecanorreceptores/fisiologia; Neuralgia/fisiopatologia; Células Receptoras Sensoriais/fisiologia; Proteína Vesicular 1 de Transporte de Glutamato/metabolismo; Animais; Feminino; Masculino; Camundongos; Camundongos Transgênicos; Optogenética/métodos; Traumatismos dos Nervos Periféricos

Palavras-chave

allodynia; neuropathic; optogenetics; pain

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células Receptoras Sensoriais / Proteína Vesicular 1 de Transporte de Glutamato / Hiperalgesia / Mecanorreceptores / Neuralgia Limite: Animals Idioma: En Revista: J Neurosci Ano de publicação: 2019 Tipo de documento: Article

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