Drug repurposing in neurological diseases: an integrated approach to reduce trial and error.

Clout, Alexander E; Della Pasqua, Oscar; Hanna, Michael G; Orlu, Mine; Pitceathly, Robert D S

Clout, Alexander E; Della Pasqua, Oscar; Hanna, Michael G; Orlu, Mine; Pitceathly, Robert D S.

Afiliação

Clout AE; Department of Pharmaceutics, UCL School of Pharmacy, London, UK.
Della Pasqua O; Clinical Pharmacology and Therapeutics Group, UCL School of Pharmacy, London, UK.
Hanna MG; Clinical Pharmacology Modelling and Simulation, GlaxoSmithKline, Uxbridge, UK.
Orlu M; MRC Centre for Neuromuscular Diseases, UCL Queen Square Institute of Neurology and National Hospital for Neurology and Neurosurgery, London, UK.
Pitceathly RDS; Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, London, UK.

J Neurol Neurosurg Psychiatry ; 90(11): 1270-1275, 2019 11.

Article em En | MEDLINE | ID: mdl-31171583

Assuntos

Reposicionamento de Medicamentos/métodos; Doenças do Sistema Nervoso/tratamento farmacológico; Humanos

Palavras-chave

Pharmacodynamics; Pharmacokinetic-Pharmacodynamic; Pharmacokinetics; clinical trials; dose rationale; formulation; neurological diseases; repositioning; repurposing

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Reposicionamento de Medicamentos / Doenças do Sistema Nervoso Limite: Humans Idioma: En Revista: J Neurol Neurosurg Psychiatry Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Reino Unido

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