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Reconstruction of Nasal Defects With Dermal Skin Substitutes-A Retrospective Study of 36 Defects.
Moratin, Katharina; Koch, Philipp-Sebastian; Benecke, Johannes; Orouji, Azadeh; Bauer, Corinne; Faulhaber, Jörg; Koenen, Wolfgang; Felcht, Moritz.
Afiliação
  • Moratin K; 1 Department of Dermatology, Venereology and Allergology, University Medical Center and Medical Faculty Mannheim, University of Heidelberg, Center of Excellence in Dermatology, Germany.
  • Koch PS; 1 Department of Dermatology, Venereology and Allergology, University Medical Center and Medical Faculty Mannheim, University of Heidelberg, Center of Excellence in Dermatology, Germany.
  • Benecke J; 2 European Center for Angioscience, Medical Faculty Mannheim, University of Heidelberg, Germany.
  • Orouji A; 1 Department of Dermatology, Venereology and Allergology, University Medical Center and Medical Faculty Mannheim, University of Heidelberg, Center of Excellence in Dermatology, Germany.
  • Bauer C; 1 Department of Dermatology, Venereology and Allergology, University Medical Center and Medical Faculty Mannheim, University of Heidelberg, Center of Excellence in Dermatology, Germany.
  • Faulhaber J; 1 Department of Dermatology, Venereology and Allergology, University Medical Center and Medical Faculty Mannheim, University of Heidelberg, Center of Excellence in Dermatology, Germany.
  • Koenen W; 3 Division of Vascular Oncology and Metastasis, German Cancer Research Center (DKFZ-ZMBH Alliance), Heidelberg, Germany.
  • Felcht M; 4 Department of Vascular Biology and Tumor Angiogenesis (CBTM), Medical Faculty Mannheim, Heidelberg University, Germany.
J Cutan Med Surg ; 23(4): 413-420, 2019.
Article em En | MEDLINE | ID: mdl-31179746
OBJECTIVES: It is uncertain whether dermal regeneration templates (DRTs) are helpful to reconstruct nasal defects. The aim of this study was to assess whether the aesthetic subunits determine the outcome. METHODS: In this unicentric, retrospective study, the surgical procedures and outcomes of patients who received DRTs to reconstruct nasal defects were assessed and compared with the involved aesthetic subunits. RESULTS: DRTs were used for reconstruction of 36 nasal defects in 35 patients with involvement of 76 aesthetic subunits: nasal sidewall (n = 21), nasal ala (n = 13), nasal tip/columella (n = 12, n = 1, respectively), nasal dorsum (n = 12), and extranasal aesthetic areas (n = 17). Fifty-eight nasal and 8 extranasal aesthetic subunits were reconstructed with DRTs, 10 subunits with a flap. Twenty-nine of 36 defects healed without any complications (80.5%). All reconstructed nasal tips/columella and the nasal dorsa healed without any complications. Region-specific complications were retraction of the ala rim (4/12; 33.3% of the patients with involvement of the nasal ala) and the formation of a fistula in the nasal sidewall (1/21; 4.8%). Region-specific complications of extranasal subunits were the development of an ectropium (2/3; 66.7% of the patients with involvement of the lower lid). CONCLUSIONS: DRTs can be helpful to reconstruct nasal defects. However, if the defect involves the aesthetic subunits nasal ala or the infraorbital region, different techniques should be preferred.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Rinoplastia / Neoplasias Cutâneas / Deformidades Adquiridas Nasais / Neoplasias Nasais / Pele Artificial / Ferida Cirúrgica Tipo de estudo: Observational_studies Limite: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: J Cutan Med Surg Assunto da revista: DERMATOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Alemanha

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Rinoplastia / Neoplasias Cutâneas / Deformidades Adquiridas Nasais / Neoplasias Nasais / Pele Artificial / Ferida Cirúrgica Tipo de estudo: Observational_studies Limite: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: J Cutan Med Surg Assunto da revista: DERMATOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Alemanha