Some naturally occurring compounds that increase longevity and stress resistance in model organisms of aging.
Biogerontology
; 20(5): 583-603, 2019 10.
Article
em En
| MEDLINE
| ID: mdl-31187283
ABSTRACT
Humans and other organisms show age-related signs of deterioration, which makes aging an interesting process to study. In the present work, we review the anti-aging evidence of several of the most promising natural compounds. Quercetin, rapamycin, resveratrol, spermidine, curcumin or sulforaphane administration increase longevity and stress resistance in model organisms such as yeasts, nematodes, flies and mice. Even more, rapamycin, resveratrol, and curcumin are currently in preclinical tests on the Interventions Testing Program of the National Institute on Aging due to their encouraging results in model organisms. The potential mechanisms underlying the beneficial effects of these compounds are briefly described.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Produtos Biológicos
/
Envelhecimento
/
Adaptação Fisiológica
/
Transdução de Sinais
/
Longevidade
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Biogerontology
Assunto da revista:
GERIATRIA
Ano de publicação:
2019
Tipo de documento:
Article
País de afiliação:
México