SIRT7 mediates L1 elements transcriptional repression and their association with the nuclear lamina.

Vazquez, Berta N; Thackray, Joshua K; Simonet, Nicolas G; Chahar, Sanjay; Kane-Goldsmith, Noriko; Newkirk, Simon J; Lee, Suman; Xing, Jinchuan; Verzi, Michael P; An, Wenfeng; Vaquero, Alejandro; Tischfield, Jay A; Serrano, Lourdes

Vazquez, Berta N; Thackray, Joshua K; Simonet, Nicolas G; Chahar, Sanjay; Kane-Goldsmith, Noriko; Newkirk, Simon J; Lee, Suman; Xing, Jinchuan; Verzi, Michael P; An, Wenfeng; Vaquero, Alejandro; Tischfield, Jay A; Serrano, Lourdes.

Afiliação

Vazquez BN; Department of Genetics, Human Genetics Institute of New Jersey, Rutgers University, Piscataway, NJ 08854, USA.
Thackray JK; Chromatin Biology Laboratory, Josep Carreras Leukaemia Research Institute, Badalona, Barcelona 08916, Spain.
Simonet NG; Department of Genetics, Human Genetics Institute of New Jersey, Rutgers University, Piscataway, NJ 08854, USA.
Chahar S; Chromatin Biology Laboratory, Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), Barcelona 08908, Spain.
Kane-Goldsmith N; Department of Genetics, Human Genetics Institute of New Jersey, Rutgers University, Piscataway, NJ 08854, USA.
Newkirk SJ; Montpellier Institute of Molecular Genetics (IGMM), CNRS and the University of Montpellier, 34090, France.
Lee S; Department of Genetics, Human Genetics Institute of New Jersey, Rutgers University, Piscataway, NJ 08854, USA.
Xing J; Department of Pharmaceutical Sciences, College of Pharmacy and Allied Health Professions, South Dakota State University, Brookings, SD 57007, USA.
Verzi MP; Department of Pharmaceutical Sciences, College of Pharmacy and Allied Health Professions, South Dakota State University, Brookings, SD 57007, USA.
An W; Department of Genetics, Human Genetics Institute of New Jersey, Rutgers University, Piscataway, NJ 08854, USA.
Vaquero A; Department of Genetics, Human Genetics Institute of New Jersey, Rutgers University, Piscataway, NJ 08854, USA.
Tischfield JA; Department of Pharmaceutical Sciences, College of Pharmacy and Allied Health Professions, South Dakota State University, Brookings, SD 57007, USA.
Serrano L; Chromatin Biology Laboratory, Josep Carreras Leukaemia Research Institute, Badalona, Barcelona 08916, Spain.

Nucleic Acids Res ; 47(15): 7870-7885, 2019 09 05.

Article em En | MEDLINE | ID: mdl-31226208

Assuntos

Genoma; Lamina Tipo A/genética; Elementos Nucleotídeos Longos e Dispersos; Sirtuínas/genética; Transcrição Gênica; Animais; Linhagem Celular; Linhagem Celular Tumoral; Imunoprecipitação da Cromatina; Epigênese Genética; Fibroblastos/citologia; Fibroblastos/metabolismo; Heterocromatina/química; Heterocromatina/metabolismo; Histonas/genética; Histonas/metabolismo; Humanos; Células K562; Lamina Tipo A/metabolismo; Fígado/citologia; Fígado/metabolismo; Masculino; Camundongos; Camundongos Knockout; Miocárdio/citologia; Miocárdio/metabolismo; Lâmina Nuclear/metabolismo; Lâmina Nuclear/ultraestrutura; Sirtuínas/deficiência; Sirtuínas/metabolismo; Testículo/citologia; Testículo/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transcrição Gênica / Genoma / Elementos Nucleotídeos Longos e Dispersos / Sirtuínas / Lamina Tipo A Tipo de estudo: Risk_factors_studies Limite: Animals / Humans / Male Idioma: En Revista: Nucleic Acids Res Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos

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