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Genetic studies of abdominal MRI data identify genes regulating hepcidin as major determinants of liver iron concentration.
Wilman, Henry R; Parisinos, Constantinos A; Atabaki-Pasdar, Naeimeh; Kelly, Matt; Thomas, E Louise; Neubauer, Stefan; Mahajan, Anubha; Hingorani, Aroon D; Patel, Riyaz S; Hemingway, Harry; Franks, Paul W; Bell, Jimmy D; Banerjee, Rajarshi; Yaghootkar, Hanieh.
Afiliação
  • Wilman HR; Research Centre for Optimal Health, School of Life Sciences, University of Westminster, London, UK; Perspectum Diagnostics Ltd., Oxford, UK.
  • Parisinos CA; Institute of Health Informatics, Faculty of Population Health Sciences, University College London, London, UK. Electronic address: c.parisinos@ucl.ac.uk.
  • Atabaki-Pasdar N; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Skåne University Hospital Malmö, Malmö, Sweden.
  • Kelly M; Perspectum Diagnostics Ltd., Oxford, UK.
  • Thomas EL; Research Centre for Optimal Health, School of Life Sciences, University of Westminster, London, UK.
  • Neubauer S; Perspectum Diagnostics Ltd., Oxford, UK; Oxford Centre for Clinical Magnetic Resonance Research, Division of Cardiovascular Medicine, Oxford NIHR Biomedical Research Centre, University of Oxford, Oxford, UK.
  • Mahajan A; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.
  • Hingorani AD; Institute of Cardiovascular Science, Faculty of Population Health Sciences, University College London, London, UK.
  • Patel RS; Institute of Cardiovascular Science, Faculty of Population Health Sciences, University College London, London, UK.
  • Hemingway H; Institute of Health Informatics, Faculty of Population Health Sciences, University College London, London, UK.
  • Franks PW; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Skåne University Hospital Malmö, Malmö, Sweden.
  • Bell JD; Oxford Centre for Clinical Magnetic Resonance Research, Division of Cardiovascular Medicine, Oxford NIHR Biomedical Research Centre, University of Oxford, Oxford, UK.
  • Banerjee R; Perspectum Diagnostics Ltd., Oxford, UK.
  • Yaghootkar H; Research Centre for Optimal Health, School of Life Sciences, University of Westminster, London, UK; Genetics of Complex Traits, College of Medicine and Health, University of Exeter, Exeter, UK. Electronic address: h.yaghootkar@exeter.ac.uk.
J Hepatol ; 71(3): 594-602, 2019 09.
Article em En | MEDLINE | ID: mdl-31226389
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Estudo de Associação Genômica Ampla / Hepcidinas / Proteína da Hemocromatose / Hemocromatose / Ferro / Fígado Tipo de estudo: Clinical_trials / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged País/Região como assunto: Europa Idioma: En Revista: J Hepatol Assunto da revista: GASTROENTEROLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Estudo de Associação Genômica Ampla / Hepcidinas / Proteína da Hemocromatose / Hemocromatose / Ferro / Fígado Tipo de estudo: Clinical_trials / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged País/Região como assunto: Europa Idioma: En Revista: J Hepatol Assunto da revista: GASTROENTEROLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Reino Unido