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Pharmacologic inhibition of LIMK1 provides dendritic spine resilience against ß-amyloid.
Henderson, Benjamin W; Greathouse, Kelsey M; Ramdas, Raksha; Walker, Courtney K; Rao, Tejeshwar C; Bach, Svitlana V; Curtis, Kendall A; Day, Jeremy J; Mattheyses, Alexa L; Herskowitz, Jeremy H.
Afiliação
  • Henderson BW; Center for Neurodegeneration and Experimental Therapeutics, University of Alabama at Birmingham School of Medicine, Birmingham, AL 35294, USA.
  • Greathouse KM; Department of Neurology, University of Alabama at Birmingham School of Medicine, Birmingham, AL 35294, USA.
  • Ramdas R; Center for Neurodegeneration and Experimental Therapeutics, University of Alabama at Birmingham School of Medicine, Birmingham, AL 35294, USA.
  • Walker CK; Department of Neurology, University of Alabama at Birmingham School of Medicine, Birmingham, AL 35294, USA.
  • Rao TC; Center for Neurodegeneration and Experimental Therapeutics, University of Alabama at Birmingham School of Medicine, Birmingham, AL 35294, USA.
  • Bach SV; Department of Neurology, University of Alabama at Birmingham School of Medicine, Birmingham, AL 35294, USA.
  • Curtis KA; Center for Neurodegeneration and Experimental Therapeutics, University of Alabama at Birmingham School of Medicine, Birmingham, AL 35294, USA.
  • Day JJ; Department of Neurology, University of Alabama at Birmingham School of Medicine, Birmingham, AL 35294, USA.
  • Mattheyses AL; Department of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham School of Medicine, Birmingham, AL 35294, USA.
  • Herskowitz JH; Department of Neurobiology, University of Alabama at Birmingham School of Medicine, Birmingham, AL 35294, USA.
Sci Signal ; 12(587)2019 06 25.
Article em En | MEDLINE | ID: mdl-31239325
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fragmentos de Peptídeos / Transdução de Sinais / Peptídeos beta-Amiloides / Espinhas Dendríticas / Inibidores de Proteínas Quinases / Quinases Lim / Doença de Alzheimer Limite: Animals / Humans Idioma: En Revista: Sci Signal Assunto da revista: CIENCIA / FISIOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fragmentos de Peptídeos / Transdução de Sinais / Peptídeos beta-Amiloides / Espinhas Dendríticas / Inibidores de Proteínas Quinases / Quinases Lim / Doença de Alzheimer Limite: Animals / Humans Idioma: En Revista: Sci Signal Assunto da revista: CIENCIA / FISIOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos