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An Azo Coupling Strategy for Protein 3-Nitrotyrosine Derivatization.
Liu, Yuxin; Zhou, Pengcheng; Da, Honghong; Jia, Huiyi; Bai, Feifei; Hu, Guodong; Zhang, Baoxin; Fang, Jianguo.
Afiliação
  • Liu Y; State Key Laboratory of Applied Organic Chemistry &, College of Chemistry and Chemical Engineering, Lanzhou University, No. 222 South Tianshui Road, Lanzhou, 730000, China.
  • Zhou P; College of Chemistry & Materials Science, South-Central University for Nationalities, No. 708 Minyuan Road, Wuhan, 430074, China.
  • Da H; State Key Laboratory of Applied Organic Chemistry &, College of Chemistry and Chemical Engineering, Lanzhou University, No. 222 South Tianshui Road, Lanzhou, 730000, China.
  • Jia H; State Key Laboratory of Applied Organic Chemistry &, College of Chemistry and Chemical Engineering, Lanzhou University, No. 222 South Tianshui Road, Lanzhou, 730000, China.
  • Bai F; State Key Laboratory of Applied Organic Chemistry &, College of Chemistry and Chemical Engineering, Lanzhou University, No. 222 South Tianshui Road, Lanzhou, 730000, China.
  • Hu G; State Key Laboratory of Applied Organic Chemistry &, College of Chemistry and Chemical Engineering, Lanzhou University, No. 222 South Tianshui Road, Lanzhou, 730000, China.
  • Zhang B; State Key Laboratory of Applied Organic Chemistry &, College of Chemistry and Chemical Engineering, Lanzhou University, No. 222 South Tianshui Road, Lanzhou, 730000, China.
  • Fang J; State Key Laboratory of Applied Organic Chemistry &, College of Chemistry and Chemical Engineering, Lanzhou University, No. 222 South Tianshui Road, Lanzhou, 730000, China.
Chemistry ; 25(48): 11228-11232, 2019 Aug 27.
Article em En | MEDLINE | ID: mdl-31241789
ABSTRACT
Herein, a strategy for the selective derivatization of 3-nitrotyrosine-containing proteins using the classic azo coupling reaction as the key step is described. This novel approach featured multiple advantages and was successfully applied to detect picomole levels of protein tyrosine nitration in biological samples.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: Chemistry Assunto da revista: QUIMICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China

Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: Chemistry Assunto da revista: QUIMICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China