Neuroprotection induced by Navß2­knockdown in APP/PS1 transgenic neurons is associated with NEP regulation.

Hu, Tao; Li, Shan-Shan; Lu, Min-Nan; Zhang, Li; Chen, Bo; Mao, Rui; Mei, Rong; Tan, Ya-Xin; Li, Shan; Xiyang, Yan-Bin

Neuroprotection induced by Navß2knockdown in APP/PS1 transgenic neurons is associated with NEP regulation.

Hu, Tao; Li, Shan-Shan; Lu, Min-Nan; Zhang, Li; Chen, Bo; Mao, Rui; Mei, Rong; Tan, Ya-Xin; Li, Shan; Xiyang, Yan-Bin.

Afiliação

Hu T; Institute of Neuroscience, Basic Medical College, Kunming Medical University, Kunming, Yunnan 650500, P.R. China.
Li SS; Basic Medical College, Kunming Medical University, Kunming, Yunnan 650500, P.R. China.
Lu MN; Experiment Center for Medical Science Research, Kunming Medical University, Kunming, Yunnan 650500, P.R. China.
Zhang L; Editorial Department of Journal of Kunming Medical University, Kunming, Yunnan 650500, P.R. China.
Chen B; Experiment Center for Medical Science Research, Kunming Medical University, Kunming, Yunnan 650500, P.R. China.
Mao R; School of Stomatology, Kunming Medical University, Kunming, Yunnan 650500, P.R. China.
Mei R; Department of Neurology, The First People's Hospital of Yunnan Province, Kunming, Yunnan 650032, P.R. China.
Tan YX; Institute of Neuroscience, Basic Medical College, Kunming Medical University, Kunming, Yunnan 650500, P.R. China.
Li S; Institute of Neuroscience, Basic Medical College, Kunming Medical University, Kunming, Yunnan 650500, P.R. China.
Xiyang YB; Institute of Neuroscience, Basic Medical College, Kunming Medical University, Kunming, Yunnan 650500, P.R. China.

Mol Med Rep ; 20(2): 2002-2011, 2019 Aug.

Article em En | MEDLINE | ID: mdl-31257483

Assuntos

Neurônios/metabolismo; Neuroproteção/genética; Presenilina-1/genética; Subunidade beta-2 do Canal de Sódio Disparado por Voltagem/genética; Precursor de Proteína beta-Amiloide/genética; Animais; Modelos Animais de Doenças; Hipocampo/metabolismo; Hipocampo/patologia; Humanos; Camundongos; Camundongos Transgênicos; Mutação; Neprilisina/genética; Neurônios/patologia; Regiões Promotoras Genéticas/genética

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Presenilina-1 / Subunidade beta-2 do Canal de Sódio Disparado por Voltagem / Neuroproteção / Neurônios Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: Mol Med Rep Ano de publicação: 2019 Tipo de documento: Article

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