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Mibefradil, a T-type Ca2+ channel blocker also blocks Orai channels by action at the extracellular surface.
Li, Pengyun; Rubaiy, Hussein N; Chen, Gui-Lan; Hallett, Thomas; Zaibi, Nawel; Zeng, Bo; Saurabh, Rahul; Xu, Shang-Zhong.
Afiliação
  • Li P; Centre for Atherothrombosis and Metabolic Disease, Hull York Medical School, University of Hull, Hull, UK.
  • Rubaiy HN; Key Laboratory of Medical Electrophysiology, Ministry of Education, and Institute of Cardiovascular Research, Southwest Medical University, Luzhou, China.
  • Chen GL; Centre for Atherothrombosis and Metabolic Disease, Hull York Medical School, University of Hull, Hull, UK.
  • Hallett T; Centre for Atherothrombosis and Metabolic Disease, Hull York Medical School, University of Hull, Hull, UK.
  • Zaibi N; Key Laboratory of Medical Electrophysiology, Ministry of Education, and Institute of Cardiovascular Research, Southwest Medical University, Luzhou, China.
  • Zeng B; Centre for Atherothrombosis and Metabolic Disease, Hull York Medical School, University of Hull, Hull, UK.
  • Saurabh R; Centre for Atherothrombosis and Metabolic Disease, Hull York Medical School, University of Hull, Hull, UK.
  • Xu SZ; Key Laboratory of Medical Electrophysiology, Ministry of Education, and Institute of Cardiovascular Research, Southwest Medical University, Luzhou, China.
Br J Pharmacol ; 176(19): 3845-3856, 2019 10.
Article em En | MEDLINE | ID: mdl-31271653

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Bloqueadores dos Canais de Cálcio / Canais de Cálcio / Mibefradil / Proteína ORAI1 / Proteína ORAI2 Limite: Humans Idioma: En Revista: Br J Pharmacol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Reino Unido

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Bloqueadores dos Canais de Cálcio / Canais de Cálcio / Mibefradil / Proteína ORAI1 / Proteína ORAI2 Limite: Humans Idioma: En Revista: Br J Pharmacol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Reino Unido