Crystal structure, epitope, and functional impact of an antibody against a superactive FVIIa provide insights into allosteric mechanism.

Jiang, Longguang; Xie, Xie; Li, Jinyu; Persson, Egon; Huang, Mingdong

Jiang, Longguang; Xie, Xie; Li, Jinyu; Persson, Egon; Huang, Mingdong.

Afiliação

Jiang L; College of Chemistry National & Local Joint Biomedical Engineering Research Center on Photodynamic Technologies Fuzhou University Fuzhou China.
Xie X; College of Chemistry National & Local Joint Biomedical Engineering Research Center on Photodynamic Technologies Fuzhou University Fuzhou China.
Li J; College of Chemistry National & Local Joint Biomedical Engineering Research Center on Photodynamic Technologies Fuzhou University Fuzhou China.
Persson E; Haemophilia Biology Novo Nordisk A/S Novo Nordisk Park Måløv, Denmark.
Huang M; College of Chemistry National & Local Joint Biomedical Engineering Research Center on Photodynamic Technologies Fuzhou University Fuzhou China.

Res Pract Thromb Haemost ; 3(3): 412-419, 2019 Jul.

Article em En | MEDLINE | ID: mdl-31294329

Palavras-chave

SAXS; antibody; blood coagulation; crystal structure; factor VIIa; inhibition

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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: Res Pract Thromb Haemost Ano de publicação: 2019 Tipo de documento: Article

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