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Humanized anti-CD271 monoclonal antibody exerts an anti-tumor effect by depleting cancer stem cells.
Morita, Shinkichi; Mochizuki, Mai; Wada, Kouichi; Shibuya, Rie; Nakamura, Mao; Yamaguchi, Kazunori; Yamazaki, Tomoko; Imai, Takayuki; Asada, Yukinori; Matsuura, Kazuto; Sugamura, Kazuo; Katori, Yukio; Satoh, Kennichi; Tamai, Keiichi.
Afiliação
  • Morita S; Division of Cancer Stem Cell, Miyagi Cancer Center Research Institute, 47-1, Medeshima-Shiode, Natori, Miyagi, Japan; Department of Head and Neck Surgery, Miyagi Cancer Center, 47-1, Medeshima-Shiode, Natori, Miyagi, Japan.
  • Mochizuki M; Division of Cancer Stem Cell, Miyagi Cancer Center Research Institute, 47-1, Medeshima-Shiode, Natori, Miyagi, Japan.
  • Wada K; Research Unit/Innovative Medical Science, Sohyaku, Innovative Research Division, Mitsubishi Tanabe Pharma Corporation, 1000, Kamoshida-cho, Aoba-ku, Yokohama, Kanagawa, Japan.
  • Shibuya R; Division of Cancer Stem Cell, Miyagi Cancer Center Research Institute, 47-1, Medeshima-Shiode, Natori, Miyagi, Japan.
  • Nakamura M; Division of Molecular and Cellular Oncology, Miyagi Cancer Center Research Institute, 47-1, Medeshima-Shiode, Natori, Miyagi, Japan.
  • Yamaguchi K; Division of Molecular and Cellular Oncology, Miyagi Cancer Center Research Institute, 47-1, Medeshima-Shiode, Natori, Miyagi, Japan.
  • Yamazaki T; Department of Head and Neck Medical Oncology, Miyagi Cancer Center, 47-1, Medeshima-Shiode, Natori, Miyagi, Japan.
  • Imai T; Department of Head and Neck Surgery, Miyagi Cancer Center, 47-1, Medeshima-Shiode, Natori, Miyagi, Japan.
  • Asada Y; Department of Head and Neck Surgery, Miyagi Cancer Center, 47-1, Medeshima-Shiode, Natori, Miyagi, Japan.
  • Matsuura K; Department of Head and Neck Surgery, Miyagi Cancer Center, 47-1, Medeshima-Shiode, Natori, Miyagi, Japan.
  • Sugamura K; Division of Molecular and Cellular Oncology, Miyagi Cancer Center Research Institute, 47-1, Medeshima-Shiode, Natori, Miyagi, Japan.
  • Katori Y; Department of Otolaryngology-Head and Neck Surgery, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi, Japan.
  • Satoh K; Division of Cancer Stem Cell, Miyagi Cancer Center Research Institute, 47-1, Medeshima-Shiode, Natori, Miyagi, Japan; Division of Gastroenterology and Hepatology, Tohoku Medical and Pharmaceutical University, 4-4-1 Komatsushima, Aobaku, Sendai, Miyagi, Japan.
  • Tamai K; Division of Cancer Stem Cell, Miyagi Cancer Center Research Institute, 47-1, Medeshima-Shiode, Natori, Miyagi, Japan. Electronic address: tamaikeiichi@med.tohoku.ac.jp.
Cancer Lett ; 461: 144-152, 2019 Oct 01.
Article em En | MEDLINE | ID: mdl-31325530
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células-Tronco Neoplásicas / Neoplasias Hipofaríngeas / Receptores de Fator de Crescimento Neural / Anticorpos Monoclonais Humanizados / Neoplasias Pulmonares / Melanoma / Citotoxicidade Celular Dependente de Anticorpos / Proteínas do Tecido Nervoso Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Cancer Lett Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Japão
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células-Tronco Neoplásicas / Neoplasias Hipofaríngeas / Receptores de Fator de Crescimento Neural / Anticorpos Monoclonais Humanizados / Neoplasias Pulmonares / Melanoma / Citotoxicidade Celular Dependente de Anticorpos / Proteínas do Tecido Nervoso Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Cancer Lett Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Japão