Screening and surgical prophylaxis for hereditary cancer syndromes with high risk of endometrial and ovarian cancer.
J Surg Oncol
; 120(5): 864-872, 2019 Oct.
Article
em En
| MEDLINE
| ID: mdl-31355450
ABSTRACT
In the era of advanced cancer genomics, our recognition of hereditary cancer mutations continues to increase. Two of these conditions, which carry an increased risk of female cancers including endometrial, ovarian, breast, are hereditary breast and ovarian cancer syndrome and Lynch syndrome. Risk-reducing surgery, such as mastectomy, salpingo-oophorectomy, and hysterectomy may decrease cancer risk for mutation carriers. Background, indications, techniques, and consequences of these surgical procedures are reviewed.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Ovarianas
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Procedimentos Cirúrgicos Operatórios
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Síndromes Neoplásicas Hereditárias
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Neoplasias do Endométrio
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Predisposição Genética para Doença
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Detecção Precoce de Câncer
Tipo de estudo:
Diagnostic_studies
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Etiology_studies
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Prevalence_studies
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Risk_factors_studies
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Screening_studies
Limite:
Female
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Humans
Idioma:
En
Revista:
J Surg Oncol
Ano de publicação:
2019
Tipo de documento:
Article