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A Novel Assessment Tool for Impulsive Aggression in Children with Attention-Deficit/Hyperactivity Disorder.
Ceresoli-Borroni, Gianpiera; Liranso, Tesfaye; Brittain, Scott T; Connor, Daniel F; Evans, Christopher J; Findling, Robert L; Hwang, Steve; Candler, Shawn A; Robb, Adelaide S; Nasser, Azmi; Schwabe, Stefan.
Afiliação
  • Ceresoli-Borroni G; Department of Clinical Research, Supernus Pharmaceuticals, Inc., Rockville, Maryland.
  • Liranso T; Department of Clinical Research, Supernus Pharmaceuticals, Inc., Rockville, Maryland.
  • Brittain ST; Department of Clinical Research, Supernus Pharmaceuticals, Inc., Rockville, Maryland.
  • Connor DF; Department of Psychiatry, Division of Child and Adolescent Psychiatry, University of Connecticut School of Medicine, Farmington, Connecticut.
  • Evans CJ; Department of Research Science, Endpoint Outcomes, Boston, Massachusetts.
  • Findling RL; Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University, Baltimore, Maryland.
  • Hwang S; Department of Psychiatry and Behavioral Sciences, Kennedy Krieger Institute, Baltimore, Maryland.
  • Candler SA; Department of Research Science, Endpoint Outcomes, Boston, Massachusetts.
  • Robb AS; Department of Medical Affairs, Supernus Pharmaceuticals, Inc., Rockville, Maryland.
  • Nasser A; Department of Psychiatry and Behavioral Sciences, Children's National Medical Center, Washington, District of Columbia.
  • Schwabe S; Department of Psychiatry and Behavioral Sciences, George Washington University, Washington, District of Columbia.
J Child Adolesc Psychopharmacol ; 29(8): 592-598, 2019 10.
Article em En | MEDLINE | ID: mdl-31369291
ABSTRACT

Objective:

To establish the validity and reliability of a provisional 30-item impulsive aggression (IA) diary in children (ages 6-12 years, inclusive) with attention-deficit/hyperactivity disorder (ADHD).

Methods:

The provisional 30-item IA diary was administered for 14 days to parents of children with ADHD and IA symptoms (n = 103). Key inclusion criteria confirmed ADHD diagnosis; signs of IA as measured by a Retrospective-Modified Overt Aggression Scale (R-MOAS) score ≥20 and an Aggression Questionnaire score of -2 to -5. Analyses included inter-item correlations, exploratory factor analysis (EFA), item response theory (IRT) modeling, internal consistency, test-retest reliability (TRT), concurrent validity (estimated by correlation between the IA diary and the R-MOAS/Nisonger Child Behavior Rating Form), and known-groups methods.

Results:

The prevalence rates of 15 (50.0%) items were found to be too low (<1%) for analysis; three items with prevalence rates ≤1% were retained, as content validity was deemed high by clinical experts. The remaining 12 behavior items had prevalence rates of 2.7%-73.6%. EFA and IRT models confirmed two subdomains in the IA diary included within a general domain of IA behavior frequency, yielding a single total behavioral frequency score (TBFS). Internal consistency was high for this TBFS (marginal reliability = 0.86 and α = 0.73). TRT for the TBFS, based on the intraclass correlation coefficient, was 0.8. Concurrent validity of TBFS with R-MOAS ranged from r = 0.49 to r = 0.62.

Conclusion:

The final 15-item IA diary is a reliable, psychometrically validated IA measurement tool that will allow clinicians and researchers to assess the frequency of IA behavior.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Escalas de Graduação Psiquiátrica / Transtorno do Deficit de Atenção com Hiperatividade / Inquéritos e Questionários / Agressão / Comportamento Impulsivo Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Child / Female / Humans / Male Idioma: En Revista: J Child Adolesc Psychopharmacol Assunto da revista: PEDIATRIA / PSICOFARMACOLOGIA Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Escalas de Graduação Psiquiátrica / Transtorno do Deficit de Atenção com Hiperatividade / Inquéritos e Questionários / Agressão / Comportamento Impulsivo Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Child / Female / Humans / Male Idioma: En Revista: J Child Adolesc Psychopharmacol Assunto da revista: PEDIATRIA / PSICOFARMACOLOGIA Ano de publicação: 2019 Tipo de documento: Article