Effect of the Resveratrol Rice DJ526 on Longevity.
Nutrients
; 11(8)2019 Aug 05.
Article
em En
| MEDLINE
| ID: mdl-31387244
ABSTRACT
Resveratrol is the best-known chemical for extending the lifespan of various organisms. Extensive recent research has shown that resveratrol can extend the lifespan of single-celled organisms, but its effects on the extension of animal lifespans are marginal. Despite the limited efficacy of pure resveratrol, resveratrol with the endogenous property of the DJ rice in the resveratrol rice DJ526 previously showed profound health benefits. Here, we report that the resveratrol rice DJ526 markedly extended the lifespan of the fruit fly Drosophila melanogaster by as much as 41.4% compared to that of the control. The resveratrol rice DJ526 also improved age-related symptoms such as locomotive deterioration, body weight gain, eye degeneration and neurodegeneration in D. melanogaster upon aging. This result shows the most significantly improved lifespan in animal experiments to date, meaning that the resveratrol rice DJ526 will assist in the development of a therapeutic agent for longevity or addressing age-related degeneration.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Oryza
/
Alimentos Fortificados
/
Drosophila melanogaster
/
Resveratrol
/
Longevidade
Limite:
Animals
Idioma:
En
Revista:
Nutrients
Ano de publicação:
2019
Tipo de documento:
Article