Long-term outcomes of preterm infants treated with less invasive surfactant technique (LISA).
J Matern Fetal Neonatal Med
; 34(12): 1919-1924, 2021 Jun.
Article
em En
| MEDLINE
| ID: mdl-31405313
ABSTRACT
OBJECTIVE:
The aim of this study is to compare the clinical outcomes at 24 months postmenstrual age of two populations receiving beractant replacement therapy using less invasive surfactant administration (LISA) versus intubation, administration of surfactant, and early extubation (INSURE). Hospital admission requirements, psychomotor development, and respiratory and neurological outcomes were studied. STUDYDESIGN:
This was a single-center, retrospective, and descriptive study with a sample of 60 patients (30 for each group) on nasal continuous positive airway pressure during the first 3 days of life, requiring surfactant administration.RESULTS:
We found no significant differences between both groups on psychomotor development and respiratory and neurological outcomes.CONCLUSION:
Compared to INSURE technique, the administration of surfactant by LISA is feasible and safe and reduces invasive mechanical ventilation exposure with no differences in the follow-up neurodevelopmental and respiratory outcomes at 24 postmenstrual age.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Síndrome do Desconforto Respiratório do Recém-Nascido
/
Tensoativos
Tipo de estudo:
Observational_studies
Limite:
Humans
/
Infant
/
Newborn
Idioma:
En
Revista:
J Matern Fetal Neonatal Med
Assunto da revista:
OBSTETRICIA
/
PERINATOLOGIA
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Espanha