Are nanotechnological approaches the future of treating inflammatory diseases?
Nanomedicine (Lond)
; 14(17): 2379-2390, 2019 09.
Article
em En
| MEDLINE
| ID: mdl-31414616
ABSTRACT
The current treatments for chronic inflammatory diseases cause severe side effects due to nonspecific drug accumulation. Nanotechnology opens the way to new therapeutic strategies that exploit the ability of immune cells, and especially of phagocytes, to internalize nanoparticles. The cellular uptake of nanoparticles requires specific interactions and is affected by the chemical and physical properties of the carriers. Therefore, optimizing these properties is crucial for designing nanodrugs for immunotherapy. In perspective, we discuss the nanoparticle-based approaches that have been proposed to induce tolerance in autoimmune disorders and lessen the symptoms of inflammatory diseases.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Doenças Autoimunes
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Nanopartículas
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Inflamação
Limite:
Animals
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Humans
Idioma:
En
Revista:
Nanomedicine (Lond)
Ano de publicação:
2019
Tipo de documento:
Article
País de afiliação:
Itália