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PI3K/AKT inhibitors aggravate death receptor-mediated hepatocyte apoptosis and liver injury.
Liu, Wei; Jing, Zhen-Tang; Xue, Chao-Rong; Wu, Shu-Xiang; Chen, Wan-Nan; Lin, Xin-Jian; Lin, Xu.
Afiliação
  • Liu W; Key Laboratory of Gastrointestinal Cancer (Fujian Medical University), Ministry of Education, Fuzhou, China; Fujian Key Laboratory of Tumor Microbiology, Department of Medical Microbiology, Fujian Medical University, Fuzhou, China.
  • Jing ZT; Key Laboratory of Gastrointestinal Cancer (Fujian Medical University), Ministry of Education, Fuzhou, China.
  • Xue CR; Key Laboratory of Gastrointestinal Cancer (Fujian Medical University), Ministry of Education, Fuzhou, China.
  • Wu SX; Key Laboratory of Gastrointestinal Cancer (Fujian Medical University), Ministry of Education, Fuzhou, China.
  • Chen WN; Key Laboratory of Gastrointestinal Cancer (Fujian Medical University), Ministry of Education, Fuzhou, China; Fujian Key Laboratory of Tumor Microbiology, Department of Medical Microbiology, Fujian Medical University, Fuzhou, China.
  • Lin XJ; Key Laboratory of Gastrointestinal Cancer (Fujian Medical University), Ministry of Education, Fuzhou, China.
  • Lin X; Key Laboratory of Gastrointestinal Cancer (Fujian Medical University), Ministry of Education, Fuzhou, China; Fujian Key Laboratory of Tumor Microbiology, Department of Medical Microbiology, Fujian Medical University, Fuzhou, China. Electronic address: linxu@mail.fjmu.edu.cn.
Toxicol Appl Pharmacol ; 381: 114729, 2019 10 15.
Article em En | MEDLINE | ID: mdl-31445927
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Apoptose / Hepatócitos / Inibidores de Proteínas Quinases / Proteínas Proto-Oncogênicas c-akt / Doença Hepática Induzida por Substâncias e Drogas / Inibidores de Fosfoinositídeo-3 Quinase Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Toxicol Appl Pharmacol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China
Texto completo
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XML
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Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Apoptose / Hepatócitos / Inibidores de Proteínas Quinases / Proteínas Proto-Oncogênicas c-akt / Doença Hepática Induzida por Substâncias e Drogas / Inibidores de Fosfoinositídeo-3 Quinase Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Toxicol Appl Pharmacol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China