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Synthesis of new indazole based dual inhibitors of α-glucosidase and α-amylase enzymes, their in vitro, in silico and kinetics studies.
Rafique, Rafaila; Khan, Khalid Mohammed; Chigurupati, Sridevi; Wadood, Abdul; Rehman, Ashfaq Ur; Karunanidhi, Arunkumar; Hameed, Shehryar; Taha, Muhammad; Al-Rashida, Mariya.
Afiliação
  • Rafique R; H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan.
  • Khan KM; H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan; Department of Clinical Pharmacy, Institute for Research and Medical Consultations (IRMC), Imam Abdulrahman Bin Faisal University, P.O. Box 31441, Dammam,
  • Arshia; H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan.
  • Kanwal; H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan.
  • Chigurupati S; Department of Pharmacology, Faculty of Pharmacy, Qassim University, Buraidah 52571, Saudi Arabia.
  • Wadood A; Department of Biochemistry, Shankar Campus, Abdul Wali Khan University, Mardan, Khyber Pukhtoonkhwa, Pakistan.
  • Rehman AU; Department of Biochemistry, Shankar Campus, Abdul Wali Khan University, Mardan, Khyber Pukhtoonkhwa, Pakistan.
  • Karunanidhi A; Department of Medical Microbiology and Parasitology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia.
  • Hameed S; H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan.
  • Taha M; Department of Clinical Pharmacy, Institute for Research and Medical Consultations (IRMC), Imam Abdulrahman Bin Faisal University, P.O. Box 31441, Dammam, Saudi Arabia.
  • Al-Rashida M; Department of Chemistry, Forman Christian College (A Chartered University), Lahore, Pakistan.
Bioorg Chem ; 94: 103195, 2020 01.
Article em En | MEDLINE | ID: mdl-31451297
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores Enzimáticos / Alfa-Amilases / Inibidores de Glicosídeo Hidrolases / Indazóis Idioma: En Revista: Bioorg Chem Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Paquistão
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores Enzimáticos / Alfa-Amilases / Inibidores de Glicosídeo Hidrolases / Indazóis Idioma: En Revista: Bioorg Chem Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Paquistão