Mice Discriminate Stereoscopic Surfaces Without Fixating in Depth.
J Neurosci
; 39(41): 8024-8037, 2019 10 09.
Article
em En
| MEDLINE
| ID: mdl-31462533
ABSTRACT
Stereopsis is a ubiquitous feature of primate mammalian vision, but little is known about if and how rodents such as mice use stereoscopic vision. We used random dot stereograms to test for stereopsis in male and female mice, and they were able to discriminate near from far surfaces over a range of disparities, with diminishing performance for small and large binocular disparities. Based on two-photon measurements of disparity tuning, the range of disparities represented in the visual cortex aligns with the behavior and covers a broad range of disparities. When we examined their binocular eye movements, we found that, unlike primates, mice did not systematically vary relative eye positions or use vergence eye movements when presented with different disparities. Nonetheless, the representation of disparity tuning was wide enough to capture stereoscopic information over a range of potential vergence angles. Although mice share fundamental characteristics of stereoscopic vision with primates and carnivores, their lack of disparity-dependent vergence eye movements and wide neuronal representation suggests that they may use a distinct strategy for stereopsis.SIGNIFICANCE STATEMENT Binocular vision allows us to derive depth information by comparing right and left eye information. We characterized binocular integration in mice because tools exist in these animals to dissect the underlying neural circuitry for binocular vision. Using random dot stereograms, we find that behavior and disparity tuning in the visual cortex share fundamental characteristics with primates, but we did not observe any evidence of disparity-dependent changes in vergence angle. We propose that mice use a distinct strategy of stereopsis compared with primates by using a broad range of disparities to encode depth over a large field of view and to compensate for nonstereoscopic changes in vergence angle that arise during natural behavior.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Percepção de Profundidade
/
Discriminação Psicológica
Tipo de estudo:
Prognostic_studies
Limite:
Animals
Idioma:
En
Revista:
J Neurosci
Ano de publicação:
2019
Tipo de documento:
Article