Oral administration of recombinant Bacillus subtilis spores expressing Helicobacter pylori neutrophil-activating protein suppresses peanut allergy via up-regulation of Tregs.

Mai, Jialiang; Liang, Bingshao; Xiong, Zhile; Ai, Xiaolan; Gao, Fei; Long, Yan; Yao, Shuwen; Liu, Yunfeng; Gong, Sitang; Zhou, Zhenwen

Mai, Jialiang; Liang, Bingshao; Xiong, Zhile; Ai, Xiaolan; Gao, Fei; Long, Yan; Yao, Shuwen; Liu, Yunfeng; Gong, Sitang; Zhou, Zhenwen.

Afiliação

Mai J; Clinical Laboratory, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
Liang B; Clinical Laboratory, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
Xiong Z; Clinical Laboratory, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
Ai X; Clinical Laboratory, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
Gao F; Clinical Laboratory, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
Long Y; Clinical Laboratory, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
Yao S; Clinical Laboratory, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
Liu Y; Clinical Laboratory, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
Gong S; Pediatric Gastroenterology Department, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
Zhou Z; Clinical Laboratory, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.

Clin Exp Allergy ; 49(12): 1605-1614, 2019 12.

Article em En | MEDLINE | ID: mdl-31468633

Assuntos

Bacillus subtilis; Proteínas de Bactérias; Helicobacter pylori/genética; Microrganismos Geneticamente Modificados; Hipersensibilidade a Amendoim; Esporos Bacterianos; Linfócitos T Reguladores/imunologia; Administração Oral; Animais; Bacillus subtilis/genética; Bacillus subtilis/imunologia; Proteínas de Bactérias/genética; Proteínas de Bactérias/imunologia; Feminino; Camundongos; Microrganismos Geneticamente Modificados/genética; Microrganismos Geneticamente Modificados/imunologia; Hipersensibilidade a Amendoim/imunologia; Hipersensibilidade a Amendoim/terapia; Esporos Bacterianos/genética; Esporos Bacterianos/imunologia; Linfócitos T Reguladores/patologia

Palavras-chave

Bacillus subtilis spores; Treg; intestinal microbiota; neutrophil-activating protein; peanut allergy

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Esporos Bacterianos / Bacillus subtilis / Proteínas de Bactérias / Helicobacter pylori / Linfócitos T Reguladores / Hipersensibilidade a Amendoim / Microrganismos Geneticamente Modificados Limite: Animals Idioma: En Revista: Clin Exp Allergy Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China

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