Development of a conserved chimeric vaccine based on helper T-cell and CTL epitopes for induction of strong immune response against Schistosoma mansoni using immunoinformatics approaches.

Rahmani, Abolfazl; Baee, Masoud; Rostamtabar, Maryam; Karkhah, Ahmad; Alizadeh, Solmaz; Tourani, Mehdi; Nouri, Hamid Reza

Rahmani, Abolfazl; Baee, Masoud; Rostamtabar, Maryam; Karkhah, Ahmad; Alizadeh, Solmaz; Tourani, Mehdi; Nouri, Hamid Reza.

Afiliação

Rahmani A; Student Research Committee, Babol University of Medical Sciences, Babol, Iran.
Baee M; Student Research Committee, Babol University of Medical Sciences, Babol, Iran.
Rostamtabar M; Cellular and Molecular Biology Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
Karkhah A; Cellular and Molecular Biology Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
Alizadeh S; Student Research Committee, Babol University of Medical Sciences, Babol, Iran.
Tourani M; Immunoregulation Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
Nouri HR; Cellular and Molecular Biology Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran; Immunoregulation Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran. Electronic address: h.noori@mubabol.ac.ir.

Int J Biol Macromol ; 141: 125-136, 2019 Dec 01.

Article em En | MEDLINE | ID: mdl-31479669

Assuntos

Antígenos de Helmintos; Epitopos de Linfócito T; Schistosoma mansoni; Linfócitos T Citotóxicos/imunologia; Linfócitos T Auxiliares-Indutores/imunologia; Vacinas; Animais; Antígenos de Helmintos/química; Antígenos de Helmintos/imunologia; Epitopos de Linfócito B/química; Epitopos de Linfócito B/imunologia; Epitopos de Linfócito T/química; Epitopos de Linfócito T/imunologia; Humanos; Schistosoma mansoni/química; Schistosoma mansoni/imunologia; Esquistossomose mansoni/imunologia; Esquistossomose mansoni/prevenção & controle; Vacinas/química; Vacinas/imunologia

Palavras-chave

Chimeric vaccine; Immunoinformatics; Schistosoma mansoni

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Schistosoma mansoni / Vacinas / Linfócitos T Citotóxicos / Linfócitos T Auxiliares-Indutores / Epitopos de Linfócito T / Antígenos de Helmintos Limite: Animals / Humans Idioma: En Revista: Int J Biol Macromol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Irã

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