Association between mid-upper arm circumference and cardiometabolic risk in Chinese population: a cross-sectional study.
BMJ Open
; 9(9): e028904, 2019 09 08.
Article
em En
| MEDLINE
| ID: mdl-31501106
ABSTRACT
OBJECTIVES:
Upper body fat has been associated with an unfavourable cardiometabolic risk. We aimed to investigate the associations between mid-upper arm circumference (MUAC), a novel indicator of upper body fat, and a wide spectrum of cardiometabolic risk profiles in Chinese population. DESIGN ANDSETTING:
Cross-sectional analyses were performed using data from a well-defined community in 2014, Shanghai, China.PARTICIPANTS:
A total of 6287 Chinese adults (2310 men and 3977 women) aged 40 years or older. OUTCOMEMEASURES:
Multivariable logistic regression model was used to examine the associations of MUAC with cardiometabolic disorders including central obesity, diabetes, hypertension, hypertriglyceridaemia, low high-density lipoprotein (HDL) cholesterol and subclinical atherosclerosis.RESULTS:
In the overall participants, after multivariable adjustment, each 1 SD (3.13 cm) increment in MUAC was positively associated with central obesity (OR 2.05; 95% CI 1.85 to 2.28), hypertension (OR 1.10; 95% CI 1.03 to 1.19) and low HDL cholesterol (OR 1.10; 95% CI 1.01 to 1.22). Multivariable-adjusted ORs for subclinical atherosclerosis were gradually increased across increasing quartiles of MUAC with the lowest quartile as reference (quartile 2 OR 1.31; 95% CI 1.09 to 1.58; quartile 3 OR 1.33; 95% CI 1.10 to 1.62; quartile 4 OR 1.45; 95% CI 1.16 to 1.80; p for trend=0.005). Similar but more prominent associations were observed among women than men. In addition, MUAC was significantly interacted with diabetes (p for interaction=0.04) and insulin resistance (p for interaction=0.01) on subclinical atherosclerosis.CONCLUSION:
A greater MUAC was positively associated with higher risks of several cardiometabolic disorders and subclinical atherosclerosis in Chinese adults.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Braço
/
Hipertrigliceridemia
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Diabetes Mellitus Tipo 2
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Aterosclerose
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Distribuição da Gordura Corporal
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Obesidade Abdominal
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Hipercolesterolemia
/
Hipertensão
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Prevalence_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Aged
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Female
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Humans
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Male
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Middle aged
País/Região como assunto:
Asia
Idioma:
En
Revista:
BMJ Open
Ano de publicação:
2019
Tipo de documento:
Article