Successful treatment of co-existent SAPHO syndrome and hidradenitis suppurativa with adalimumab and methotrexate.
J Eur Acad Dermatol Venereol
; 33 Suppl 6: 40-41, 2019 Oct.
Article
em En
| MEDLINE
| ID: mdl-31535768
ABSTRACT
SAPHO syndrome, namely Synovitis, Acne, Pustulosis, Hyperostosis and Osteitis, is a rare autoinflammatory chronic disease presenting with non-infectious inflammatory osteitis, sterile joint inflammation and skin manifestations, including palmoplantar pustulosis and severe acne. The case of a 15-year-old boy affected by SAPHO syndrome and hidradenitis suppurativa (HS) is presented and discussed. Coexistence of these two diseases may represent a therapeutic challenge and this case confirms literature data reporting the efficacy of the combination of methotrexate and adalimumab in SAPHO complicated by HS.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Metotrexato
/
Hidradenite Supurativa
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Síndrome de Hiperostose Adquirida
/
Fármacos Dermatológicos
/
Adalimumab
/
Anti-Inflamatórios
Limite:
Adolescent
/
Humans
/
Male
Idioma:
En
Revista:
J Eur Acad Dermatol Venereol
Assunto da revista:
DERMATOLOGIA
/
DOENCAS SEXUALMENTE TRANSMISSIVEIS
Ano de publicação:
2019
Tipo de documento:
Article
País de afiliação:
Itália