FGF23 and inflammation-a vicious coalition in CKD.
Kidney Int
; 96(4): 813-815, 2019 10.
Article
em En
| MEDLINE
| ID: mdl-31543148
ABSTRACT
High serum concentrations of the phosphaturic hormone, fibroblast growth factor 23 (FGF23), contribute to various tissue injuries. In chronic kidney disease, the sources of FGF23 and the stimuli that control FGF23 production differ from those in the physiologic scenario. Mediators of inflammation are intensively studied as potential factors that contribute to FGF23 elevations and thereby might function as drug targets to lower FGF23 levels. The present study focuses on tumor necrosis factor.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Insuficiência Renal Crônica
/
Hipofosfatemia Familiar
Limite:
Humans
Idioma:
En
Revista:
Kidney Int
Ano de publicação:
2019
Tipo de documento:
Article
País de afiliação:
Estados Unidos