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Germline-Encoded Affinity for Cognate Antigen Enables Vaccine Amplification of a Human Broadly Neutralizing Response against Influenza Virus.
Sangesland, Maya; Ronsard, Larance; Kazer, Samuel W; Bals, Julia; Boyoglu-Barnum, Seyhan; Yousif, Ashraf S; Barnes, Ralston; Feldman, Jared; Quirindongo-Crespo, Maricel; McTamney, Patrick M; Rohrer, Daniel; Lonberg, Nils; Chackerian, Bryce; Graham, Barney S; Kanekiyo, Masaru; Shalek, Alex K; Lingwood, Daniel.
Afiliação
  • Sangesland M; The Ragon Institute of Massachusetts General Hospital, The Massachusetts Institute of Technology and Harvard University, 400 Technology Square, Cambridge, MA 02139, USA.
  • Ronsard L; The Ragon Institute of Massachusetts General Hospital, The Massachusetts Institute of Technology and Harvard University, 400 Technology Square, Cambridge, MA 02139, USA.
  • Kazer SW; The Ragon Institute of Massachusetts General Hospital, The Massachusetts Institute of Technology and Harvard University, 400 Technology Square, Cambridge, MA 02139, USA; Institute for Medical Engineering and Science (IMES), Department of Chemistry, and Koch Institute for Integrative Cancer Research,
  • Bals J; The Ragon Institute of Massachusetts General Hospital, The Massachusetts Institute of Technology and Harvard University, 400 Technology Square, Cambridge, MA 02139, USA.
  • Boyoglu-Barnum S; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, NIH, 40 Convent Drive, Bethesda, MD 20892-3005, USA.
  • Yousif AS; The Ragon Institute of Massachusetts General Hospital, The Massachusetts Institute of Technology and Harvard University, 400 Technology Square, Cambridge, MA 02139, USA.
  • Barnes R; Bristol-Myers Squibb, 700 Bay Road, Redwood City, CA 94063-2478, USA.
  • Feldman J; The Ragon Institute of Massachusetts General Hospital, The Massachusetts Institute of Technology and Harvard University, 400 Technology Square, Cambridge, MA 02139, USA.
  • Quirindongo-Crespo M; Bristol-Myers Squibb, 700 Bay Road, Redwood City, CA 94063-2478, USA.
  • McTamney PM; Medimmune LLC, One MedImmune Way, Gaithersburg, MD 20878, USA.
  • Rohrer D; Bristol-Myers Squibb, 700 Bay Road, Redwood City, CA 94063-2478, USA.
  • Lonberg N; Bristol-Myers Squibb, 700 Bay Road, Redwood City, CA 94063-2478, USA.
  • Chackerian B; Department of Molecular Genetics and Microbiology, University of New Mexico School of Medicine, 2425 Camino de Salud, Albuquerque, NM 87106, USA.
  • Graham BS; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, NIH, 40 Convent Drive, Bethesda, MD 20892-3005, USA.
  • Kanekiyo M; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, NIH, 40 Convent Drive, Bethesda, MD 20892-3005, USA.
  • Shalek AK; The Ragon Institute of Massachusetts General Hospital, The Massachusetts Institute of Technology and Harvard University, 400 Technology Square, Cambridge, MA 02139, USA; Institute for Medical Engineering and Science (IMES), Department of Chemistry, and Koch Institute for Integrative Cancer Research,
  • Lingwood D; The Ragon Institute of Massachusetts General Hospital, The Massachusetts Institute of Technology and Harvard University, 400 Technology Square, Cambridge, MA 02139, USA. Electronic address: dlingwood@mgh.harvard.edu.
Immunity ; 51(4): 735-749.e8, 2019 10 15.
Article em En | MEDLINE | ID: mdl-31563464
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vírus da Influenza A / Vacinas contra Influenza / Linfócitos B / Receptores de Antígenos de Linfócitos B / Influenza Humana / Anticorpos Amplamente Neutralizantes / Anticorpos Antivirais Limite: Animals / Humans Idioma: En Revista: Immunity Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vírus da Influenza A / Vacinas contra Influenza / Linfócitos B / Receptores de Antígenos de Linfócitos B / Influenza Humana / Anticorpos Amplamente Neutralizantes / Anticorpos Antivirais Limite: Animals / Humans Idioma: En Revista: Immunity Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos