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Neohesperidin inhibits TGF-ß1/Smad3 signaling and alleviates bleomycin-induced pulmonary fibrosis in mice.
Guo, Jiasen; Fang, Yinshan; Jiang, Fangxin; Li, Lian; Zhou, Honggang; Xu, Xiaojun; Ning, Wen.
Afiliação
  • Guo J; State Key Laboratory of Medicinal Chemical Biology, College of Life Sciences, Nankai University, Tianjin, 300071, China.
  • Fang Y; State Key Laboratory of Medicinal Chemical Biology, College of Life Sciences, Nankai University, Tianjin, 300071, China.
  • Jiang F; State Key Laboratory of Medicinal Chemical Biology, College of Life Sciences, Nankai University, Tianjin, 300071, China.
  • Li L; State Key Laboratory of Medicinal Chemical Biology, College of Life Sciences, Nankai University, Tianjin, 300071, China; Respiratory Department, Tianjin Medical University General Hospital, Tianjin, 300071, China.
  • Zhou H; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Nankai University, Tianjin, 300071, China.
  • Xu X; State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, 211198, China. Electronic address: xiaojunxu2000@163.com.
  • Ning W; State Key Laboratory of Medicinal Chemical Biology, College of Life Sciences, Nankai University, Tianjin, 300071, China. Electronic address: ningwen108@nankai.edu.cn.
Eur J Pharmacol ; 864: 172712, 2019 Dec 01.
Article em En | MEDLINE | ID: mdl-31586469
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fibrose Pulmonar / Bleomicina / Transdução de Sinais / Proteína Smad3 / Fator de Crescimento Transformador beta1 / Hesperidina Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Eur J Pharmacol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fibrose Pulmonar / Bleomicina / Transdução de Sinais / Proteína Smad3 / Fator de Crescimento Transformador beta1 / Hesperidina Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Eur J Pharmacol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China