Cold-adapted bacterial extracts as a source of anti-infective and antimicrobial compounds against Staphylococcus aureus.
Future Microbiol
; 14: 1369-1382, 2019 11.
Article
em En
| MEDLINE
| ID: mdl-31596138
ABSTRACT
Aim:
The dramatic emergence of antibiotic resistance has directed the interest of research toward the discovery of novel antimicrobial molecules. In this context, cold-adapted marine bacteria living in polar regions represent an untapped reservoir of biodiversity endowed with an interesting chemical repertoire. The aim of this work was to identify new antimicrobials and/or antibiofilm molecules produced by cold-adapted bacteria. Materials &methods:
Organic extracts obtained from polar marine bacteria were tested against Staphylococcus aureus. Most promising samples were subjected to suitable purification strategies.Results:
Results obtained led to the identification of a novel lipopeptide able to effectively inhibit the biofilm formation of S. aureus.Conclusion:
New lipopeptide may be potentially useful in a wide variety of biotechnological and medical applications.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Staphylococcus aureus
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Bactérias
/
Temperatura Baixa
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Biofilmes
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Anti-Infecciosos
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Antibacterianos
Idioma:
En
Revista:
Future Microbiol
Assunto da revista:
MICROBIOLOGIA
Ano de publicação:
2019
Tipo de documento:
Article
País de afiliação:
Itália