3p involvement in a renal cell carcinoma in von Hippel-Lindau syndrome. Region of tumor breakpoint clustering on 3p?

The cytogenetic findings in a renal cell carcinoma from a patient with von Hippel-Lindau syndrome are reported. Of the two consistent changes, one was a dicentric chromosome evolving from an unbalanced translocation between the proximal part of the short arm of chromosome 3 and the distal segment of the long arm of the X chromosome.