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PEGylation but Not Fc-Fusion Improves in Vivo Residence Time of a Thermostable Mutant of Bacterial Cocaine Esterase.
Huang, Haifeng; Fang, Lei; Xue, Liu; Zhang, Ting; Kim, Kyungbo; Hou, Shurong; Zheng, Fang; Zhan, Chang-Guo.
Afiliação
  • Huang H; Molecular Modeling and Biopharmaceutical Center, College of Pharmacy , University of Kentucky , Lexington , Kentucky 40536 , United States.
  • Fang L; Department of Pharmaceutical Sciences, College of Pharmacy , University of Kentucky , Lexington , Kentucky 40536 , United States.
  • Xue L; Department of Pharmaceutical Sciences, College of Pharmacy , University of Kentucky , Lexington , Kentucky 40536 , United States.
  • Zhang T; Department of Pharmaceutical Sciences, College of Pharmacy , University of Kentucky , Lexington , Kentucky 40536 , United States.
  • Kim K; Molecular Modeling and Biopharmaceutical Center, College of Pharmacy , University of Kentucky , Lexington , Kentucky 40536 , United States.
  • Hou S; Department of Pharmaceutical Sciences, College of Pharmacy , University of Kentucky , Lexington , Kentucky 40536 , United States.
  • Zheng F; Molecular Modeling and Biopharmaceutical Center, College of Pharmacy , University of Kentucky , Lexington , Kentucky 40536 , United States.
  • Zhan CG; Department of Pharmaceutical Sciences, College of Pharmacy , University of Kentucky , Lexington , Kentucky 40536 , United States.
Bioconjug Chem ; 30(12): 3021-3027, 2019 12 18.
Article em En | MEDLINE | ID: mdl-31661952
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Polietilenoglicóis / Estabilidade Enzimática / Hidrolases de Éster Carboxílico Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Bioconjug Chem Assunto da revista: BIOQUIMICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Polietilenoglicóis / Estabilidade Enzimática / Hidrolases de Éster Carboxílico Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Bioconjug Chem Assunto da revista: BIOQUIMICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos