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DJ-1 can form ß-sheet structured aggregates that co-localize with pathological amyloid deposits.
Solti, Katalin; Kuan, Wei-Li; Fórizs, Balázs; Kustos, Gergely; Mihály, Judith; Varga, Zoltán; Herberth, Balázs; Moravcsik, Éva; Kiss, Róbert; Kárpáti, Manuela; Mikes, Anna; Zhao, Yanyan; Imre, Tímea; Rochet, Jean-Christophe; Aigbirhio, Franklin; Williams-Gray, Caroline H; Barker, Roger A; Tóth, Gergely.
Afiliação
  • Solti K; TTK-NAP B - Drug Discovery Research Group - Neurodegenerative Diseases, Institute of Organic Chemistry, Research Center for Natural Sciences, Budapest, Hungary.
  • Kuan WL; John van Geest Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge, Forvie Site, Robinson Way, Cambridge CB2 0PY, UK.
  • Fórizs B; TTK-NAP B - Drug Discovery Research Group - Neurodegenerative Diseases, Institute of Organic Chemistry, Research Center for Natural Sciences, Budapest, Hungary; Cantabio Pharmaceuticals, Palo Alto, CA, USA.
  • Kustos G; Cantabio Pharmaceuticals, Palo Alto, CA, USA.
  • Mihály J; Institute of Materials and Environmental Chemistry Research Centre for Natural Sciences, Budapest, Hungary.
  • Varga Z; Institute of Materials and Environmental Chemistry Research Centre for Natural Sciences, Budapest, Hungary.
  • Herberth B; TTK-NAP B - Drug Discovery Research Group - Neurodegenerative Diseases, Institute of Organic Chemistry, Research Center for Natural Sciences, Budapest, Hungary; Cantabio Pharmaceuticals, Palo Alto, CA, USA.
  • Moravcsik É; Cantabio Pharmaceuticals, Palo Alto, CA, USA.
  • Kiss R; TTK-NAP B - Drug Discovery Research Group - Neurodegenerative Diseases, Institute of Organic Chemistry, Research Center for Natural Sciences, Budapest, Hungary.
  • Kárpáti M; Cantabio Pharmaceuticals, Palo Alto, CA, USA.
  • Mikes A; TTK-NAP B - Drug Discovery Research Group - Neurodegenerative Diseases, Institute of Organic Chemistry, Research Center for Natural Sciences, Budapest, Hungary.
  • Zhao Y; Molecular Imaging Chemistry Laboratory, Wolfson Brain Imaging Centre, Department of Clinical Neurosciences, University of Cambridge, Cambridge CB2 0QQ, UK.
  • Imre T; MS Metabolomic Research Laboratory, Institute of Organic Chemistry, Research Center for Natural Sciences, Budapest, Hungary.
  • Rochet JC; Department of Medicinal Chemistry and Molecular Pharmacology and Purdue Institute for Integrative Neuroscience, Purdue University, West Lafayette, Indiana, USA.
  • Aigbirhio F; Molecular Imaging Chemistry Laboratory, Wolfson Brain Imaging Centre, Department of Clinical Neurosciences, University of Cambridge, Cambridge CB2 0QQ, UK.
  • Williams-Gray CH; John van Geest Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge, Forvie Site, Robinson Way, Cambridge CB2 0PY, UK.
  • Barker RA; John van Geest Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge, Forvie Site, Robinson Way, Cambridge CB2 0PY, UK.
  • Tóth G; TTK-NAP B - Drug Discovery Research Group - Neurodegenerative Diseases, Institute of Organic Chemistry, Research Center for Natural Sciences, Budapest, Hungary; Cantabio Pharmaceuticals, Palo Alto, CA, USA. Electronic address: toth.gergely@ttk.hu.
Neurobiol Dis ; 134: 104629, 2020 02.
Article em En | MEDLINE | ID: mdl-31669752
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Encéfalo / Doença de Alzheimer / Agregação Patológica de Proteínas / Proteína Desglicase DJ-1 Limite: Humans Idioma: En Revista: Neurobiol Dis Assunto da revista: NEUROLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Hungria
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Encéfalo / Doença de Alzheimer / Agregação Patológica de Proteínas / Proteína Desglicase DJ-1 Limite: Humans Idioma: En Revista: Neurobiol Dis Assunto da revista: NEUROLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Hungria