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Design, synthesis, in vitro inhibition and toxicological evaluation of human carbonic anhydrases I, II and IX inhibitors in 5-nitroimidazole series.
Aspatwar, Ashok; Parvathaneni, Nanda Kumar; Barker, Harlan; Anduran, Emilie; Supuran, Claudiu T; Dubois, Ludwig; Lambin, Philippe; Parkkila, Seppo; Winum, Jean-Yves.
Afiliação
  • Aspatwar A; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
  • Parvathaneni NK; Department of Precision Medicine, The M-Lab, GROW - School for Oncology and Developmental Biology, Maastricht Comprehensive Cancer Centre, Maastricht University Medical Centre, Maastricht, The Netherlands.
  • Barker H; Institut des Biomolécules, Max Mousseron (IBMM) UMR 5247 CNRS, ENSCM, Université de Montpellier, Bâtiment de Recherche Max Mousseron, Ecole Nationale Supérieure de Montpellier, Montpellier, France.
  • Anduran E; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
  • Supuran CT; Department of Precision Medicine, The M-Lab, GROW - School for Oncology and Developmental Biology, Maastricht Comprehensive Cancer Centre, Maastricht University Medical Centre, Maastricht, The Netherlands.
  • Dubois L; Institut des Biomolécules, Max Mousseron (IBMM) UMR 5247 CNRS, ENSCM, Université de Montpellier, Bâtiment de Recherche Max Mousseron, Ecole Nationale Supérieure de Montpellier, Montpellier, France.
  • Lambin P; NEUROFARBA Department, Section of Pharmaceutical and Nutraceutical Sciences, University of Florence, Polo Scientifico, Firenze, Italy.
  • Parkkila S; Department of Precision Medicine, The M-Lab, GROW - School for Oncology and Developmental Biology, Maastricht Comprehensive Cancer Centre, Maastricht University Medical Centre, Maastricht, The Netherlands.
  • Winum JY; Department of Precision Medicine, The M-Lab, GROW - School for Oncology and Developmental Biology, Maastricht Comprehensive Cancer Centre, Maastricht University Medical Centre, Maastricht, The Netherlands.
J Enzyme Inhib Med Chem ; 35(1): 109-117, 2020 Dec.
Article em En | MEDLINE | ID: mdl-31687859

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores da Anidrase Carbônica / Anidrase Carbônica I / Anidrase Carbônica II / Anidrase Carbônica IV / Nitroimidazóis Limite: Animals / Humans Idioma: En Revista: J Enzyme Inhib Med Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Finlândia

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores da Anidrase Carbônica / Anidrase Carbônica I / Anidrase Carbônica II / Anidrase Carbônica IV / Nitroimidazóis Limite: Animals / Humans Idioma: En Revista: J Enzyme Inhib Med Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Finlândia