Pt(II) and Pd(II) complexes with a thiazoline derivative ligand: Synthesis, structural characterization, antiproliferative activity and evaluation of pro-apoptotic ability in tumor cell lines HT-29 and U-937.

Fernández-Delgado, Elena; de la Cruz-Martínez, Felipe; Galán, Carmen; Franco, Lourdes; Espino, Javier; Viñuelas-Zahínos, Emilio; Luna-Giles, Francisco; Bejarano, Ignacio

Fernández-Delgado, Elena; de la Cruz-Martínez, Felipe; Galán, Carmen; Franco, Lourdes; Espino, Javier; Viñuelas-Zahínos, Emilio; Luna-Giles, Francisco; Bejarano, Ignacio.

Afiliação

Fernández-Delgado E; Department of Physiology (Neuroimmunophysiology and Chrononutrition Research Group), University of Extremadura, 06006 Badajoz, Spain.
de la Cruz-Martínez F; Department of Organic and Inorganic Chemistry (Coordination Chemistry Group), University of Extremadura, 06006 Badajoz, Spain.
Galán C; Department of Physiology (Neuroimmunophysiology and Chrononutrition Research Group), University of Extremadura, 06006 Badajoz, Spain.
Franco L; Department of Physiology (Neuroimmunophysiology and Chrononutrition Research Group), University of Extremadura, 06006 Badajoz, Spain.
Espino J; Department of Physiology (Neuroimmunophysiology and Chrononutrition Research Group), University of Extremadura, 06006 Badajoz, Spain.
Viñuelas-Zahínos E; Department of Organic and Inorganic Chemistry (Coordination Chemistry Group), University of Extremadura, 06006 Badajoz, Spain.
Luna-Giles F; Department of Organic and Inorganic Chemistry (Coordination Chemistry Group), University of Extremadura, 06006 Badajoz, Spain. Electronic address: pacoluna@unex.es.
Bejarano I; Department of Physiology and Pharmacology, University of Cantabria, 39011 Santander, Spain. Electronic address: bejaranoi@unican.es.

J Inorg Biochem ; 202: 110870, 2020 01.

Article em En | MEDLINE | ID: mdl-31689624

Assuntos

Antineoplásicos/química; Antineoplásicos/farmacologia; Cisplatino/química; Neoplasias do Colo/tratamento farmacológico; Leucemia Mieloide Aguda/tratamento farmacológico; Compostos Organometálicos/química; Paládio/química; Tiazóis/química; Apoptose; Proliferação de Células; Neoplasias do Colo/patologia; Complexos de Coordenação/química; Humanos; Leucemia Mieloide Aguda/patologia; Células Tumorais Cultivadas

Palavras-chave

Apoptosis; HT-29; Pd(II) and Pt(II) complexes; Thiazoline; Tumor cells; U-937

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Compostos Organometálicos / Paládio / Tiazóis / Leucemia Mieloide Aguda / Cisplatino / Neoplasias do Colo / Antineoplásicos Tipo de estudo: Evaluation_studies Limite: Humans Idioma: En Revista: J Inorg Biochem Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Espanha

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